Paris Saint-Germain have been hit with a quadruple injury blow as Marquinhos, Serge Aurier, Lucas Moura and Yohan Cabaye were all forced off in their 2-2 draw with Caen.
Laurent Blanc will be disappointed with the news, which could alter his preparations for their Champions League game with Chelsea on Tuesday night.
The French manager will be unsure whether the four players will be able to recover in time for their European clash, according to Goal.com.
The injuries played a big part in their result with Caen as the reigning Ligue 1 champions conceded twice while playing with nine men in the closing stages, having used all three substitutions earlier on in the game.