Manchester United will be hoping to bounce back from their 1-0 defeat at Everton by taking three points at home against Fulham.
New signing Robin van Persie is likely to make his first start for the Red Devils after starting on the bench at Goodison Park on Monday night, with Danny Welbeck expected to make way.
Sir Alex Ferguson could once more look to Michael Carrick to patch up his threadbare defence, while Rafael is expected to come in for Antonio Valencia. Ryan Giggs may also feature in place of Nani.
Meanwhile, Martin Jol may name an unchanged lineup after his men routed Norwich City 5-0 at Craven Cottage on Saturday.
Manchester United: De Gea; Evra, Carrick, Vidic, Rafael; Scholes, Kagawa, Cleverley, Giggs; Rooney, Van Persie
Fulham: Schwarzer; Riether, Hangeland, Hughes, Riise; Duff, Diarra, Dembele, Kacaniklic; Ruiz, Petric
Sports Mole says: 3-1
