Columbus Crew vs. Cincinnati (Friday, 11.30pm)
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Two struggling MLS sides are looking to end their lengthy winless runs on Friday when the Columbus Crew host their state rivals FC Cincinnati from Lower.com Field.
The Orange-and-Blue are coming off a 4-1 defeat to the New England Revolution and are winless in their last 10 matches, while the reigning MLS Cup champions have lost their previous six games, including a 2-1 decision last weekend to the Seattle Sounders.
We say: Columbus Crew 3-0 FC Cincinnati
The Crew know that they are a lot better than their current record indicates, and they can probably afford to take a few more chances moving forward against a Cincinnati squad who are poor in the final third.
Despite their lopsided defeat last week, Cincy have been much better defensively of late, but they still have some work to do away from home, allowing 12 goals in their previous three road matches.
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Montreal vs. Toronto (Saturday, 12.30am)
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Round two of the Canadian Classique will be one of the storylines to follow on Friday when CF Montreal host Toronto at Saputo Stadium in La Belle Province.
In their last three fixtures, Montreal are unbeaten, drawing the Philadelphia Union last weekend 1-1, while TFC dropped their third straight contest on Saturday, 3-1 to Inter Miami.
We say: CF Montreal 2-1 Toronto
Montreal have done enough to get by this season, and they should not have any issues maintaining a high intensity through 90 minutes against their biggest rivals who are struggling to score.
Toronto keep digging themselves a deeper hole week after week, and it seems like this group of veterans are running out of solutions to turn their season around.
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Orlando City vs. Inter Miami (Saturday, 1.30am)
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A much improved Inter Miami side will try to earn their first three-game winning streak in franchise history on Friday when they travel to Exploria Stadium to battle their sunshine state rivals, Orlando City.
The Lions ended a four-game winless run in all competitions last Saturday, defeating the Chicago Fire 1-0, while the Herons got by Toronto 3-1 last week to move into 11th in the Eastern Conference.
We say: Orlando City 1-3 Inter Miami
Both sides have the advantage of having games in hand on the teams above them in the table, but Miami are starting to score goals at long last, whereas Orlando have only scored multiple times in two of their last 11 matches.