Stuart Lancaster has named his England team to will face Scotland in the first match of the Six Nations campaign.
Eight uncapped players will feature for the national side at Murrayfield on Saturday, with Owen Farrell, Phil Dowson and Brad Barritt due to make their debuts for the Elite side.
England skipper Chris Robshaw will start at the back alongside Tom Croft, while Dave Strettle and Charlie Hodgson remain in the side with Chris Ashton on the wing.
"We have been impressed with how the whole group has come together in the last ten days and we have done a lot of work on and off the field," Sky Sports News quotes Lancaster as saying.
"Now is the time to turn all that into a performance against Scotland that we can all be proud of. It is a massive challenge - Murrayfield, the first game of the Six Nations - but one we are relishing."
An additional five uncapped members have been included on the substitutes bench for the Six Nations opener.
England: 15 Ben Foden, 14 Chris Ashton, 13 Owen Farrell, 12 Brad Barritt, 11 David Strettle, 10 Charlie Hodgson, 9 Ben Youngs, 1 Alex Corbisiero, 2 Dylan Hartley, 3 Dan Cole, 4 Mouritz Botha, 5 Tom Palmer, 6 Tom Croft, 7 Chris Robshaw, 8 Phil Dowson
Replacements: 16 Rob Webber, 17 Matt Stevens, 18 Geoff Parling, 19 Ben Morgan, 20 Lee Dickson, 21 Jordan Turner-Hall, 22 Mike Brown