Uncapped Gloucester Rugby duo Freddie Burns and Billy Twelvetrees have been drafted in to the England squad for the QBE autumn internationals.
Burns comes in as a replacement for Harlequins centre Jordan Turner-Hall, who is struggling with an inflamed knee, while Twelvetrees will provide backup for London Irish centre Jonathan Joseph, who is carrying an ankle injury.
"Freddie has been playing well in the Aviva Premiership and, with Jordan needing to stay at Harlequins for treatment, we are keen to have a look at him," said England head coach Stuart Lancaster.
"JJ is continuing his recovery from an ankle injury and this is a good chance to get Billy in for training."
England's first match comes against Fiji on Saturday before they face Australia, South Africa and New Zealand.
