Latvia vs. Netherlands (Friday, 7.45pm)
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Netherlands will be looking to record their third Group G victory in a row when they continue their World Cup 2022 qualification campaign away to Latvia on Friday night.
Louis van Gaal's side are currently top of the section with 13 points to show from their six matches, while Latvia occupy fifth, having collected five points from their opening six fixtures.
We say: Latvia 1-2 Netherlands
Latvia are capable of making this a tricky match for the Netherlands, and we are expecting a close contest on Friday night. That said, Van Gaal's side have superior quality all over the field and should have enough to put another important three points on the board.
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Gibraltar vs. Montenegro (Friday, 7.45pm)
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Montenegro will be looking to record their third victory in Group G when they continue their World Cup 2022 qualification campaign away to Gibraltar on Friday night.
The visitors are currently fourth in the section, five points behind second-placed Norway, while Gibraltar are rock bottom, having lost all six of their group games thus far.
We say: Gibraltar 0-3 Montenegro
Gibraltar will be desperate to put a point on the board before their qualification campaign ends, but it is difficult to imagine where it would come from. Montenegro have superior quality all over the field and should prove to be far too strong for their opponents on Friday night.
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Turkey vs. Norway (Friday, 7.45pm)
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Turkey will be looking to move above Norway in Group G when the two teams continue their World Cup 2022 qualification campaigns with a clash in Istanbul on Friday night.
The home side are currently third in the section, having picked up 11 points from their opening six fixtures, while Norway have collected 13 points from their six matches to sit second behind the Netherlands.
We say: Turkey 2-1 Norway
A full-strength Norway outfit would fancy their chances of picking up a positive result on Friday, but the visitors are missing a number of important players for this match. We are expecting it to be a close contest in Istanbul but have just had to settle on a narrow victory for the home side.
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Cyprus vs. Croatia (Friday, 7.45pm)
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World Cup 2018 finalists Croatia travel to Cyprus on Friday as they continue their qualifying campaign for the 2022 tournament in Qatar.
Zlatko Dalic's side currently sit top of Group H in European qualifying, while their hosts are bottom of the group.
We say: Cyprus 0-3 Croatia
With the group's worst attack coming up against the best defence, this game should be fairly straightforward to predict. Croatia have their eyes set on qualification and will be boosted by Modric's return, so will ease past Cyprus.
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Malta vs. Slovenia (Friday, 7.45pm)
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Slovenia will be aiming to keep their slim hopes of World Cup qualification alive when they travel to Malta on Friday.
Matjaz Kek's side are fourth in Group H with seven points from six games, while their hosts are fifth with four points.
We say: Malta 0-2 Slovenia
Defeat to Croatia aside, Slovenia have looked more solid in this qualifying campaign and will see this as a must-win game. We think that this extra motivation will help them emerge victorious, but it will not be a walkover at Ta' Qali.
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Russia vs. Slovakia (Friday, 7.45pm)
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Russia will continue their push for automatic World Cup qualification when they host Slovakia on Friday.
Valeri Karpin's team are second in Group H in European qualifying after four wins from six games, while their opponents are in third.
We say: Russia 2-1 Slovakia
Valeri Karpin has made Russia tighter at the back, but Slovakia will certainly test them more than Cyprus and Malta did last month. Both sides will feel they cannot afford to drop points, so a cagey affair awaits; we are backing the hosts to secure a narrow win.
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Germany vs. Romania (Friday, 7.45pm)
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Germany welcome Romania to Hamburg's Volksparkstadion on Friday evening in the latest round of World Cup 2022 European qualifiers.
The hosts sit comfortably top of Group J, whilst their opponents have fought back from a tough start and are now battling with Armenia and North Macedonia for second place.
We say: Germany 3-1 Romania
Romania's run of clean sheets looks very likely to come to end, but they also pose more of an attacking threat than Germany's most recent opponents so Die Mannschaft may also find themselves conceding.
Nonetheless, we expect Flick's side to continue their upward trajectory and secure a comfortable win on home soil.
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> How Germany could line up against Romania
Iceland vs. Armenia (Friday, 7.45pm)
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Armenia travel to Laugardalsvollur to take on Iceland on Friday evening as the World Cup 2022 European qualifiers head towards their conclusion.
The hosts have had a poor campaign and sit fifth in the group, whilst some disappointing recent results have seen Armenia fall back towards the chasing pack for second.
We say: Iceland 1-1 Armenia
Both teams will be determined to get something from the game and they may well cancel each other out to some extent. Each side has a strong defensive unit and has struggled to score goals in recent games, so a low-scoring draw seems a strong possibility.
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Liechtenstein vs. N. Macedonia (Friday, 7.45pm)
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Liechtenstein and North Macedonia will face off at the Rheinpark Stadion in Vaduz for the latest World Cup 2022 European qualifier.
The hosts are group underdogs as ever and have picked up just a solitary point so far, whilst the visitors stand a chance of making their first ever World Cup finals.
We say: Liechtenstein 0-2 North Macedonia
North Macedonia have won all six meetings between these two sides - conceding just twice as they netted 18 times - and beat their upcoming hosts 5-0 in the reverse fixture back in March.
We expect this to be a slightly closer contest, due to Liechtenstein's recent draw and home advantage, but it should still be a comfortable three points for The Lions.
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Czech Republic vs. Wales (Friday, 7.45pm)
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Wales travel to Prague to face Czech Republic on Friday evening in a crucial World Cup 2022 qualifying clash for both sides.
The teams are level on points ahead of the game at Eden Arena in their battle for second place behind runaway Group E leaders Belgium.
We say: Czech Republic 1-1 Wales
While this is not quite do-or-die for both sides, the outcome of this game could go a long way to determining who finishes second to Belgium in Group E.
Wales won the reverse fixture in March through a late Daniel James goal, but that game was very tight, and we can see a similar type of contest here with the points being shared.
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Estonia vs. Belarus (Friday, 7.45pm)
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The bottom two sides in World Cup qualifying Group E face off at A. Le Coq Arena on Friday as Estonia play host to Belarus.
Estonia picked up an impressive point away at Wales last month, but they still trail Belarus by two points in the battle to avoid fifth place.
We say: Estonia 2-1 Belarus
Belarus beat Estonia in the reverse fixture, but since then it is Friday's hosts who have picked up the better results - not least a draw away to Wales in September.
Kondratiev's side have lost five in a row, losing by an aggregate 15-3 scoreline, and we can see them falling to yet another loss here to drop to the bottom of Group E.