West Ham vs. Newcastle (Saturday, 12.30pm)
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Newcastle United will be looking to make it four Premier League victories in a row when they head to London Stadium on Saturday afternoon to take on top-four hopefuls West Ham United.
The away side, who are now out of the relegation zone, will enter the contest off the back of a 1-0 win over Aston Villa, while West Ham played out a 2-2 draw with Leicester City at the King Power Stadium.
We say: West Ham United 1-1 Newcastle United
Make no mistake, this is a really difficult game for West Ham, with the Magpies a much-improved outfit. A few weeks ago, the Hammers would have fancied their chances of winning this match relatively comfortably, but we are backing Howe's side to claim a share of the spoils at London Stadium on Saturday.
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Arsenal vs. Brentford (Saturday, 3.00pm)
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Arsenal will be looking to boost their chances of finishing in the top four with a victory against Brentford in their Premier League clash at the Emirates Stadium on Saturday.
The Gunners will be seeking revenge against the Bees, who began life in the top flight with a surprise 2-0 home win over Mikel Arteta's men on the opening day of the season.
We say: Arsenal 1-0 Brentford
Arsenal have found it difficult to find the net in recent weeks and considering that they struggled against Brentford earlier this season, the hosts could be in for another challenging contest on Saturday.
However, with the Gunners faithful cheering them on from the stands, Arteta's men should be able to secure a narrow victory and close in on the top four.
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> How Arsenal could line up against Brentford
> Arsenal injury, suspension list vs. Brentford
Aston Villa vs. Watford (Saturday, 3.00pm)
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Two Premier League teams struggling for form will lock horns at Villa Park on Saturday afternoon when Aston Villa play host to Watford.
The Villans will be seeking revenge against the Hornets, who secured a 3-2 victory at Vicarage Road in the reverse fixture back in August.
We say: Aston Villa 2-1 Watford
Aston Villa's leaky backline should provide Watford with a decent chance of ending their four-game drought without a goal. However, the hosts will head into Saturday's fixture as the favourites and they should have enough quality in their side to claim all three points.
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Brighton vs. Burnley (Saturday, 3.00pm)
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Still seeking their first away victory of the campaign, basement club Burnley will travel to the Amex Stadium to face Brighton & Hove Albion in the Premier League on Saturday.
The Seagulls, meanwhile, have won only one of their last eight top-flight home matches, and are yet to claim maximum points in front of their own fans in 2022.
We say: Brighton & Hove Albion 2-0 Burnley
Dyche is under increased pressure to turn Burnley's fortunes around, but with the potential absence of target man Weghorst, they may struggle to carve out or convert their chances on Saturday.
Brighton, meanwhile, will be keen to bounce back from their midweek defeat and having already beaten the Clarets this season, they will be the favourites to claim maximum points on home soil.
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Crystal Palace vs. Chelsea (Saturday, 3.00pm)
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Fresh from being crowned champions of the world for the first time in their history, Chelsea return to Premier League action with a London derby against Crystal Palace at Selhurst Park on Saturday.
The match will be Chelsea's first league outing in almost a month, but they take on a Palace side still winless in the top flight so far this calendar year.
We say: Crystal Palace 1-2 Chelsea
None of the last 21 Premier League games between these two sides has finished level, and we are backing Chelsea to keep that run going with a ninth successive win over Palace on Saturday.
Indeed, Chelsea's win percentage against Palace of 76% is the highest by one team over another in Premier League history, and their Club World Cup triumph should boost them when it comes to their faltering domestic form.
Palace have not been easy to beat this season and so it is unlikely to be straightforward for the visitors, but they should have enough to earn all three points.
> Click here to read our full preview for this match
> How Chelsea could line up against Crystal Palace
> Chelsea injury, suspension list vs. Crystal Palace
> Christian Pulisic's record vs. Crystal Palace
Liverpool vs. Norwich (Saturday, 3.00pm)
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Two teams at opposite ends of the Premier League table meet on Saturday when title-chasing Liverpool welcome relegation-threatened Norwich City to Anfield.
The Reds come into the match still unbeaten in all competitions this calendar year, but face a Norwich side whose survival hopes have been significantly boosted in recent weeks.
We say: Liverpool 3-0 Norwich City
Norwich have undoubtedly improved in the past month or so, but last weekend's defeat to Man City showed that they still struggle against the very best and it may be a similar story against Liverpool this weekend.
The Reds have averaged over three goals per game during a 15-match unbeaten league run against Norwich which includes 13 wins, while across the entire history of the Premier League they boast a better goals-per-game ratio against Norwich than they do against any other club.
With Salah having rediscovered his scoring touch in midweek we can see the hosts rippling the back of the net on a few occasions again, and Norwich's attacking record this season does not give us any reason to back them getting anything in reply.
Liverpool have already beaten Norwich 3-0 on two occasions this season, and we believe that they could make it a hat-trick of convincing wins on Saturday.
> Click here to read our full preview for this match
> How Liverpool could line up against Norwich
> Liverpool injury, suspension list vs. Norwich City
Southampton vs. Everton (Saturday, 3.00pm)
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Frank Lampard will be bidding to make it back-to-back Premier League wins as Everton boss when the Toffees make the trip to St Mary's on Saturday afternoon to take on Southampton.
Everton are currently 16th in the table, boasting 22 points from 22 matches, while an improving Southampton are 10th, having picked up 29 points from their 24 league fixtures this term.
We say: Southampton 1-1 Everton
This should be a cracking match between two sides with a lot of talent in the forward areas. Southampton were excellent at Old Trafford and should be full of confidence, but Everton are an improving team under Lampard, so we are backing the points to be shared in a low-scoring draw.
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Man City vs. Spurs (Saturday, 5.30pm)
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Manchester City will be looking to further strengthen their grip on first spot in the Premier League table when they welcome Tottenham Hotspur to the Etihad Stadium on Saturday evening.
The Citizens are currently nine points clear of second-placed Liverpool at the summit, while Tottenham occupy eighth position, seven points behind fourth-placed Manchester United.
We say: Manchester City 3-1 Tottenham Hotspur
Man City have won six of their last seven home matches against Tottenham in all competitions, and we are finding it very difficult to back against the Citizens here. Spurs will be desperate to return to winning ways, but Guardiola's side are incredibly strong at the moment, so we can only see one winner here.
> Click here to read our full preview for this match
> How Tottenham could line up against Manchester City
> How Manchester City could line up against Tottenham
