Sheff Utd vs. Everton (Saturday, 12.30pm)
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Two early-season strugglers prepare for battle at Bramall Lane in Saturday's lunchtime Premier League kickoff, as Sheffield United lock horns with Everton.
While the Blades' dismal run continued with an EFL Cup exit at the hands of Lincoln City in midweek, the Toffees finally found their shooting boots to see off Doncaster Rovers 2-1.
We say: Sheffield United 1-1 Everton
Having belatedly got off the mark on the goalscoring front versus Doncaster, the Beto-led Everton can also consign their Premier League attacking woes to the past against a Sheffield United side reeling from two painful beatings in the space of a few days.
However, the Blades produced a praiseworthy display against Man City and are more than capable of recovering from a one-goal deficit to deny Everton their first maximum of the Premier League season, although a low-scoring stalemate would also prolong the hosts' own wait for top-flight success.
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Brentford vs. Bournemouth (Saturday, 3.00pm)
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Having both progressed to the third round of the EFL Cup in midweek, Brentford and Bournemouth turn their attention back to the Premier League with a 3pm Saturday kickoff at the Gtech Community Stadium.
The Bees bested Newport County on penalties in midweek, while Andoni Iraola's side came up trumps in a five-goal classic with Swansea City.
We say: Brentford 3-1 Bournemouth
A distinct failure to keep the back door closed ought to prove costly for Bournemouth at a ground where Brentford need no lessons in attacking supremacy, as Iraola's men are quickly brought crashing back down to earth.
The forward-thinking Cherries might experience a sliver of joy on the attacking front themselves, but the Bees' potent firepower should be too hot for the Cherries to handle.
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Burnley vs. Spurs (Saturday, 3.00pm)
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Two teams separated by 15 places in the embryonic Premier League table square off at Turf Moor on Saturday, as Burnley play host to Tottenham Hotspur.
While Vincent Kompany's men brushed their top-flight woes to one side in the EFL Cup in midweek, Spurs' trophyless run will continue for another few months at the very least courtesy of their loss to Fulham.
We say: Burnley 0-2 Tottenham Hotspur
Both Kompany and Postecoglou have earned and will continue to earn plaudits for their forward-thinking managerial styles, but few will expect the Burnley boss to outsmart his Australian counterpart on Saturday.
With a spate of fresh injuries to deal with, a ravaged Clarets team are destined to fall short against a fired-up Tottenham, even if Richarlison finds himself watching on from the sidelines.
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> How Tottenham could line up against Burnley
> Tottenham injury, suspension list vs. Burnley
Chelsea vs. Nott'm Forest (Saturday, 3.00pm)
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Aiming to win three competitive matches on the bounce for the first time since March, Chelsea welcome Nottingham Forest to Stamford Bridge for Saturday afternoon's Premier League battle.
Mauricio Pochettino's side scraped a 2-1 EFL Cup second-round win over AFC Wimbledon last time out, while the Tricky Trees were eliminated by Burnley at the same stage.
We say: Chelsea 2-1 Nottingham Forest
Forest may not be able to buy a win away from home at the moment, but neither Arsenal nor Man United blew Cooper's men out of the water, and nor should a new-look Chelsea XI still finding their feet under Pochettino.
However, with several of the Blues' big-name stars well-rested, the Sterling-inspired hosts can expose their visitors' frailties on the road once more to make it three wins on the trot, although it may not be too pretty.
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> How Chelsea could line up against Nottingham Forest
> Chelsea injury, suspension list vs. Nottingham Forest
Man City vs. Fulham (Saturday, 3.00pm)
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Manchester City will endeavour to preserve their perfect start to the new Premier League season when they welcome Fulham to the Etihad Stadium on Saturday afternoon.
The Citizens left it late to beat Sheffield United 2-1 away from home last weekend, while the Cottagers admirably picked up a point in a 2-2 draw with Arsenal at the Emirates Stadium in their last top-flight fixture.
We say: Manchester City 3-1 Fulham
Man City have not won each of their opening four Premier League games since 2016-17, but we believe that the Citizens will come away with maximum points on Saturday against a Fulham side whom they have had plenty of joy against over the years.
Fulham will hope to frustrate the hosts as Sheffield United did in stages last weekend and pose a threat on the counter-attack, but Guardiola's side should ultimately have enough quality to break the Cottagers down and extend their impressive winning streak at the Etihad to 18 matches.
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> How Man City could line up against Fulham
> Man City injury, suspension list vs. Fulham
Brighton vs. Newcastle (Saturday, 5.30pm)
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Two Premier League teams seeking to return to winning ways do battle at the American Express Community Stadium on Saturday evening, as Brighton & Hove Albion play host to Newcastle United.
The Seagulls and the Magpies most recently meet during the Premier League Summer Series tournament over the summer, with Eddie Howe's side running out 2-1 winners.
We say: Brighton & Hove Albion 2-2 Newcastle United
Although Brighton and Newcastle drew a blank in front of goal in this fixture last season, we believe there will be a greater level of goalmouth action this time around considering the attacking threat both teams possess. There is little to separate these two sides, though, so an entertaining score draw could be on the cards.