Feyenoord vs. Sparta (Sunday, 11.15am)
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Aiming to avoid a third consecutive Eredivisie defeat on home territory, Feyenoord play host to city rivals Sparta Rotterdam at De Kuip on Sunday.
Meanwhile, the away side head into the clash on a nine-game winless streak across all competitions and will be keen to arrest this slump in form.
We say: Feyenoord 3-1 Sparta Rotterdam
Sparta have been really abysmal of late, and it is hard to see them coming away from this one with anything. We are tipping Feyenoord to come out on top in relatively comfortable fashion.
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Groningen vs. Go Ahead Eagles (Sunday, 1.30pm)
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Groningen will be hoping to make it two victories in a row on Sunday when they host Go Ahead Eagles at the Euroborg in their latest Eredivisie fixture.
Both teams find themselves in the lower half of the table heading into the match, but a victory has the potential to propel either side into the top 10, depending on other results.
We say: Groningen 1-1 Go Ahead Eagles
This match brings together two teams that are short on confidence and momentum, with both needing to pick up a victory here to truly get going in the second half of the season.
However, the lack of goals that Go Ahead Eagles are scoring right now could prove to be an issue, but with the hosts also not in great form, a draw could be likely.
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Willem II vs. RKC Waalwijk (Sunday, 1.30pm)
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Willem II will be hoping to push away from the Eredivisie relegation zone on Sunday when they host RKC Waalwijk, with the club continuing to search for their first win since September.
The visitors could move into the top half of the table with three points this weekend, depending on other results, as they head into this match with a four-game unbeaten run.
We say: Willem II 0-3 RKC Waalwijk
Willem II are in a desperate need for points at the moment with the club struggling for form at the moment, but their lack of goals recently is something that could make this difficult for them.
That is why the visitors should be able to take three points here, especially with their recent performances and goals, proving they have the firepower to secure the victory.
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Ajax vs. Heracles (Sunday, 3.45pm)
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Eredivisie champions Ajax draw the curtain on matchday 21 of the 2021-22 campaign by welcoming Heracles to the Johan Cruyff ArenA on Sunday.
The home side are looking to record a seventh victory on the bounce, while the visitors seek to extend their unbeaten across all competitions to six matches.
We say: Ajax 4-0 Heracles
Having just recently reclaimed top stop, Ajax will be looking to pull clear of all title contenders and three points this weekend would certainly be a step in the right direction. We fancy them to cruise to a comfortable victory, scoring plenty of goals en route.