Bolton vs. Exeter (Saturday, 3.00pm)
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First place is within reach for Bolton Wanderers, who host Exeter City in League One action on Saturday at Toughsheet Community Stadium.
The Whites have reeled off five successive victories domestically and are third in the table following a 1-0 win over Blackpool two weeks ago, while Exeter are just a point above the relegation zone, losing their previous encounter, 3-0 at Fleetwood Town.
We say: Bolton Wanderers 2-0 Exeter City
The Wanderers have won matches in various ways throughout the domestic campaign, while Exeter often look unstable and inconsistent at the back, which is why we believe Bolton will continue their winning ways and push towards the top spot in the league.
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Carlisle vs. Charlton (Saturday, 3.00pm)
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Entering a new era under American ownership, Carlisle United will be aiming to throw a punch in the fight for League One survival as they welcome Charlton Athletic to Brunton Park on Saturday afternoon.
The Blues have struggled to adapt to life in the third tier, although recent developments off the field have reinvigorated supporters, while the Addicks are enjoying a decent run of form.
We say: Carlisle United 1-2 Charlton Athletic
With the Piatak family casting their eyes over the team for the first time as owners, Carlisle will be desperate to earn a victory at Brunton Park this weekend.
Charlton have got back on track after back-to-back defeats to Lincoln and Bolton Wanderers in October, and we are expecting the Addicks to win in Cumbria on Saturday.
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Cheltenham vs. Oxford Utd (Saturday, 3.00pm)
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Des Buckingham will take charge of his first game as Oxford United boss when his side take on Cheltenham Town in Saturday's League One contest.
While the U's are sitting in the League One promotion places, Cheltenham are currently languishing in the bottom four.
We say: Cheltenham Town 1-2 Oxford United
Cheltenham may have avoided defeat in their last three home league games, but we think that they will be edged out by an Oxford side that boasts best away record in the division after picking up 18 points from their eight away games.
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Derby vs. Bristol Rovers (Saturday, 3.00pm)
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Derby County will be looking to bounce back from an early FA Cup exit when they welcome Bristol Rovers to Pride Park for Saturday's League One contest.
The visitors, meanwhile, will be hoping to continue their fine spell of form after putting together a six-game unbeaten run in all competitions.
We say: Derby County 2-0 Bristol Rovers
Derby know they will be presented with a tough test on Saturday, but having won three consecutive home league games without conceding, we think they will utilise home advantage to claim maximum points against Bristol Rovers.
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Fleetwood vs. Stevenage (Saturday, 3.00pm)
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Looking to further distance themselves from their poor early-season form, Fleetwood Town will welcome high-flying Stevenage to Highbury Stadium on Saturday afternoon in League One.
The Cod Army have recorded handsome victories in their last two matches prior to the international break, while Stevenage continue to mix it with the biggest names in the third tier.
We say: Fleetwood Town 1-2 Stevenage
Following a woeful start to the season under Brown, Fleetwood have enjoyed a marked improvement in recent matches, but the visit of Stevenage will be their toughest test in a while.
Boro are displaying attacking quality and defensive solidity in equal measure so far this term, and we are expecting Evans's side to record another maximum this weekend.
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Leyton Orient vs. Wigan (Saturday, 3.00pm)
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Two League One teams in contrasting form lock horns at Brisbane Road on Saturday afternoon as Leyton Orient play host to Wigan Athletic.
February 1997 was the last time these two teams squared off, with the Latics comfortably coming out on top 5-1 on home soil when the two sides were competing in the third tier.
We say: Leyton Orient 1-2 Wigan Athletic
Both teams will be keen to claim maximum points for different reasons on Saturday, with Leyton Orient hoping to end their losing streak while Wigan attempt to build on their solid run of form.
Although the Latics have struggled away from home in League One this term, we believe they will do enough to come out on top against a struggling Orient outfit, especially with Maloney expected to recall a number of first-team regulars to his side.
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Lincoln vs. Barnsley (Saturday, 3.00pm)
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Barnsley take to the field for the first time since being thrown out of the FA Cup in midweek when they travel to Lincoln City on Saturday.
Both clubs are chasing promotion in League One, and Barnsley will look to put off-field headlines behind them against a Lincoln side under new management.
We say: Lincoln City 0-1 Barnsley
The sides have met four times in the 21st century, and the home side on the day is still yet to score, including in a 0-0 draw here last season.
Barnsley's decent defensive record suggests that record could continue in a game they may just edge to return to winning ways in the league.
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Northampton vs. Cambridge (Saturday, 3.00pm)
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Two teams teetering just above the League One relegation zone will meet on Saturday as Northampton Town host Cambridge United.
Each head into this fixture on the back of defeats in their most recent performances which they will be looking to put behind them.
We say: Northampton Town 1-1 Cambridge United
There is very little between these two teams in the league table right now with both of them having tough starts to this season.
That is something that could end up being reflected on the day in what is likely going to be a cagey match.
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Peterborough vs. Burton Albion (Saturday, 3.00pm)
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Peterborough United will be aiming to continue their strong run of form in League One when they welcome Burton Albion to London Road on Saturday afternoon.
The home side are currently fifth in the table, boasting 31 points from their opening 17 matches, while Burton occupy 13th, having picked up 20 points from their first 17 games of the season.
We say: Peterborough United 2-1 Burton Albion
Burton are certainly capable of making this an uncomfortable match for Peterborough despite their recent problems, and we are expecting a close game in terms of the scoreline. Peterborough have been in strong form in the league, though, and we are backing them to emerge victorious here.
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Portsmouth vs. Blackpool (Saturday, 3.00pm)
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Portsmouth will look to remain top of the League One table when they welcome Blackpool to Fratton Park on Saturday.
While the hosts lead second-placed Oxford by one point, eighth-placed Blackpool are currently sitting outside the top six on goal difference.
We say: Portsmouth 1-1 Blackpool
Although Blackpool have won their last three away games against Portsmouth, we think a draw may be the best they can hope for when they face a Pompey side that are unbeaten in 27 league matches.
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Shrewsbury vs. Port Vale (Saturday, 3.00pm)
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Port Vale will attempt to end their nine-game winless league run when they travel to New Meadow for Saturday's clash with Shrewsbury Town.
The hosts, meanwhile, are looking to bounce back after suffering a heavy defeat in their away meeting with Blackpool last weekend.
We say: Shrewsbury Town 3-1 Port Vale
Shrewsbury may have suffered a disappointing defeat in their away meeting with Blackpool, but after winning five of their last six competitive home matches, we think they will get the job done against Port Vale.
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Wycombe vs. Reading (Saturday, 3.00pm)
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Basement side Reading will attempt to end a nine-game winless league run when they make the short trip to Adams Park for Saturday's clash with Wycombe Wanderers.
The hosts will also be looking to end a poor run of form after failing to win any of their last five matches in League One.
We say: Wycombe Wanderers 1-1 Reading
Having lost six of their last seven league games, Reading will have their work cut out to claim a positive result at the weekend, but we think they may do enough to take a point off a Wycombe side that has failed to win any of their previous three home league matches.