Everton goalkeeper Tim Howard has been released from international duty with the United States.
The 34-year-old, who is his country's undisputed first choice, will step aside for Aston Villa's Brad Guzan for Tuesday's trip to Panama.
"Brad Guzan has earned the opportunity to start against Panama," national coach Jurgen Klinsmann told reporters at a press conference.
"He has been outstanding for Aston Villa all year, and he has been huge in the games he has played for us in World Cup qualifying.
"As I said before, we have one of the best situations in the world when it comes to our goalkeepers."
The USA have already secured their qualification for next summer's World Cup.
