For Osasuna to advance through to the quarter-finals of this season's Copa del Rey, they must overturn a two-goal deficit following the first leg between these two teams at El Sadar.
Among the goals for Valencia on that evening was former Real Madrid striker Roberto Soldado. However, because his side hold the advantage, coach Ernesto Valverde could opt to rest the Spanish international, along with a number of his key players.
With that in mind, Argentine midfielder Pablo Piatti could be included in the starting lineup.
Valencia also have one of the best home records in La Liga this season, having lost just twice at the Mestalla.
In contrast, travelling Osasuna have won just once away from home from nine attempts. They have also only scored six goals in those encounters.
Recent form
Valencia: LLWLWW
Osasuna: DDWLDL
Possible starting lineups:
Valencia: Felipe; Costa, Barragan, Rami, Cissokho; Albelda, Banega, Piatti, Parejo; Jonas, Bernat
Osasuna: Riesgo; Ruben, Echaide, Lolo, Bertran; Annan, Cejudo, Nano, Torres; Timor, Manuel
Sports Mole says: 1-0
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