Wigan Athletic manager Roberto Martinez has said that he fears Ivan Ramis has suffered a serious cruciate knee ligament injury.
The defender was stretchered off after twisting his knee in the 1-1 draw with Fulham on Saturday afternoon.
The Spaniard is yet to find out the full extent of his injury, though Martinez is predicting a lengthy lay-off.
"I wouldn't want to say anything before seeing the scans, but I fear the worst," said Martinez.
"He has damaged the ligaments in the right knee and the signs are not great. I expect the worst, cruciate ligament. We are going to take him to hospital on the way back.
"Those injuries go from six to seven months, but obviously it is impossible for me to tell yet because we need to get the scans. The manner he has done it, the way he has felt the knee opening and the pain he has got in the top of the patella tendon, I do fear the worst."
The result against Fulham leaves Wigan just outside the relegation zone on goal difference.