Bayer Leverkusen have decided to include frontman Admir Mehmedi in place of Son Heung-min as they welcome travelling Lazio in their Champions League qualifying clash.
Mehmedi is to lead Bayer's frontline alongside strike partner Stefan Kiessling, while the likes of Karim Bellarabi and Hakan Calhanoglu are to provide further creativity from midfield.
As for the visitors, Lazio have called in Stefan Radu and Keita Balde Diao, but they will be without Miroslav Klose, Lucas Biglia and Federico Marchetti, who have all been hit by injury.
The Italian side have also included former Manchester United youngster Ravel Morrison on the bench, with the 22-year-old having recovered from an injury picked up during pre-season.
Bayer Leverkusen: Leno; Hilbert, Tah, Papadopoulos, Wendell, Bender, Kramer, Calhanoglu, Mehmedi, Bellarabi, Kiessling
Subs: Donati, Ramalho, Boenisch, Ryu, Kresic, Kruse, Brandt
Lazio: Berisha; Mauricio, De Vrij, Radu, Basta, Onazi, Parolo, Lulic, Candreva, Keita, Felipe Anderson
Subs: Cataldi, Gentiletti, Kishna, Konko, Guerrieri, Morrison, Milinkovic-Savic
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