In-form Fernando Torres has been dropped to the bench for the FA Cup final, with Didier Drogba starting up front in his place.
Suarez is the lone striker for Liverpool. The Uruguayan will be supported by Stewart Downing and Craig Bellamy, who is a surprise inclusion from Kenny Dalglish after struggling to make the starting eleven in the past few weeks.
Jamie Carragher and Andy Carroll also have to make do with places on the bench for Liverpool.
Branislav Ivanovic comes in to central defence and John Mikel Obi partners Frank Lampard at the base of midfield, in place of Michael Essien.
Salomon Kalou is preferred to Daniel Sturridge in the one other change from the semi-final against Tottenham Hotspur.
Liverpool: Reina, Johnson, Agger, Skrtel, Enrique, Gerrard, Spearing, Henderson, Downing, Bellamy, Suarez.
Chelsea: Cech, Bosingwa, Ivanovic, Terry, Cole, Lampard, Mikel, Ramires, Mata, Kalou, Drogba.
