Estudiantes vs. Bragantino (Thursday, 1.00am)
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It is a clash of the top-two sides in Group C of the Copa Sudamericana when Estudiantes host Bragantino at Estadio Jorge Luis Hirschi on Wednesday evening.
Both sides have already secured their passage into the knockout stages of the competitions and will be looking to preserve their unbeaten statuses in this one.
We say: Estudiantes 2-0 Bragantino
Estudiantes come into this clash in scintillating form and should be confident of all but securing top spot in the group with a win on Wednesday evening.
Bragantino face a tough trip to Argentina, and we believe they will suffer back-to-back defeats for the first time since February to relinquish their first-placed standing in Group C.
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Blooming vs. Audax (Thursday, 1.00am)
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Blooming and Audax Italiano return to action in the Copa Sudamericana as they go head-to-head at the Estadio Ramon Tahuichi Aguilera on Thursday morning.
Having lost each of their four matches so far, the Bolivian outfit will be playing just for pride, while the visitors need a win to keep their dreams of a first-placed finish alive.
We say: Blooming 0-2 Audax Italiano
With Santos breathing down their neck, Audax Italiano must avoid a slip-up in their final two outings as they look to reach the knockout stages. Marcogiuseppe's side take on a Blooming side who have endured a forgettable campaign and we fancy them picking up all three points once again.
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Emelec vs. Guarani (Thursday, 3.00am)
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Round five of the 2022-23 Copa Sudamericana sees Ecuadorian outfit Emelec entertain the challenge of Paraguayan side Guarani at Estadio George Capwell.
The teams head into this one off the back of contrasting results in their most recent league outings but Thursday's clash promises to be an exciting watch nonetheless.
We say: Emelec 2-1 Guarani
With so much left to play for, both Emelec and Guarani are expected to be fully up for the clash as they look to secure a place in the knockout phase. We expect an entertaining affair with high attacking endeavour and a narrow win for the hosts in the end.