Valencia boss Nuno has opted to keep Paco Alcacer in his forward line as Los Che look to seal a place in the Champions League knockout phase with a win over Gent.
The Spanish giants have left Pablo Piatti on the bench, with Santi Mina likely to offer support to Alcacer in attack.
Los Che will also continue with third-choice keeper Jaume Domenech in goal, as both Diego Alves and Aussie stopper Matt Ryan remain sidelined through injury.
Meanwhile, Thomas Foket, fresh from scoring against Valencia in the reverse fixture, will start for the Belgian outfit, with Laurent Depoitre leading the line for Gent.
Gent: Sels, Mitrovic, Asare, Nielsen, Renato Neto, Kums, Saief, Dejaegere, Foket, Milicevic, Depoitre
Subs: Vandenbussche, Rafinha, Johansson, Coulibaly, Poletanovic, Raman, Simon
Valencia: Domenech, Barragan, Mustafi, Santos, Gaya, Parejo, Javi Fuego, Enzo Perez, Feghouli, Alcacer, Santi Mina
Subs: Yoel, Joao Cancelo, Rúben Vezo, Danilo, Andre Gomes, Piatti, De Paul
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