Lecce vs. Atalanta (Monday, 5.30pm)
© Reuters
Following a glorious climax to last season, Atalanta BC begin their latest league campaign on Monday, as they travel south to meet Lecce at Stadio Via del Mare.
The Europa League winners were beaten by mighty Real Madrid in the UEFA Super Cup, but now they resume domestic duties, aiming for a seventh straight win on Serie A's opening matchday.
We say: Lecce 1-1 Atalanta BC
Considering they were mainly occupied with staying afloat in Serie A, Lecce lost only seven times on home turf last season, and Atalanta will not be relishing a first-day trip to Via del Mare.
La Dea's run-in to their opening league game has not been ideal either, while the hosts already have a morale-boosting cup win under their belts.
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Juventus vs. Como (Monday, 7.45pm)
© Imago
A new season starts under new management for Serie A giants Juventus, as they host promoted Como on Monday evening.
After a summer of change, the Thiago Motta era now begins in earnest - but Juve's ambitious opponents will be intent on spoiling the party.
We say: Juventus 2-0 Como
Juventus have won more Serie A openers than any other club - including seven wins across their last eight - and they should do so for a 60th time on Monday.
As Como will take time to adapt to their new surroundings, a Juve side hungry to impress under new management can ruthlessly exploit their visitors' weaknesses.