Lecce vs. AC Milan (Saturday, 2.00pm)
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Days after a crucial win in Europe, AC Milan return to domestic duty on Saturday afternoon, when they visit Lecce at Stadio Via del Mare.
While Milan started sluggishly in the Champions League and have recently faltered in Serie A, their midweek success against Paris Saint-Germain will erase memories of a four-match winless streak; their hosts, meanwhile, have not won since September.
We say: Lecce 1-2 AC Milan
Lecce's downward spiral could continue this weekend, as Milan are on a high from their Champions League heroics and have a point to prove in Serie A. While the hosts are far harder to beat on home soil, they rarely score more than once and will also be vulnerable to the Rossoneri's varied attack.
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Juventus vs. Cagliari (Saturday, 5.00pm)
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After winning five games from six without conceding a goal, Juventus have announced themselves as genuine Scudetto contenders, and they tackle in-form Cagliari on Saturday evening.
Juve have ascended to second in the Serie A standings by grimly grinding out results; meanwhile, their Sardinian counterparts have scored eight times across three recent wins.
We say: Juventus 2-0 Cagliari
Although they have finally found a way to win, Cagliari have conceded more goals from open play than any other Serie A side this season (18), and they are not the most obvious candidate to end their hosts' superb sequence of clean sheets. Victory would put Juventus top of the table - if only for a day - and that should inspire them to avoid any complacency.
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Monza vs. Torino (Saturday, 7.45pm)
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Monza could be leapfrogged by Torino in the Serie A table when they face off in a round 12 clash at the U-Power Stadium on Saturday.
Both sides head into the encounter undefeated in the previous two gameweeks, with the away side claiming consecutive victories.
We say: Monza 1-1 Torino
The spoils could be shared at the U-Power Stadium, with both sides cancelling each other out.