Lille coach Rene Girard has made one change to his side following their draw with Lyon in Ligue 1 last weekend.
Marko Basa drops out of the squad altogether and is replaced in the starting lineup by David Rozenhal.
Ajaccio boss Fabrizio Ravanelli has opted to make three alterations to the team that were held by Montpellier last time out.
Stefan Popescu, Salim Arrache and Goncalves make way for Grenddy Perozo, Benoit Pedretti and Aboubacar Demba Camara.
Lille: Enyeama, Beria, Kjaer, Rozenhal, Souare, Balmont, Gueye, Martin, Mavuba, Kalou, Roux
Ajaccio: Ochoa, Crescenzi, Dielna, Perozo, Zubar, Andre, Cavalli, Lasne, Mostefa, Pedretti, Camara
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