Paul Pogba, Matthijs de Ligt and Isco are all reportedly being monitored by Juventus ahead of the summer transfer window.
With Manchester United missing out on Champions League qualification after their 1-1 draw at Huddersfield Town on Sunday, Pogba may be more open to a move away from Old Trafford for the second time in his career.
Nineteen-year-old Ajax captain de Ligt has been the star of his side's impressive season both domestically and in Europe, leading the Eredivisie table and reaching the semi-finals of the Champions League.
Isco has been linked with a move away from Real Madrid on several occasions, with clubs such as Arsenal and Manchester City reportedly interested in the Spanish winger.
According to the Daily Mail, Juventus sporting director Fabio Paratici is eyeing up a move for all three this summer.
The report also adds that Juventus could make moves for Paris Saint-Germain's Adrien Rabiot, Lyon's Tanguy Ndombele and Real Madrid loanee James Rodriguez.
The Serie A champions faced a disappointing exit from the Champions League this season, losing to Ajax 3-2 on aggregate in the quarter-final.