Rennes boss Philippe Montanier has made three adjustments to his side that beat Evian TG last Saturday.
Sylvain Armand, Vincent Pajot and Wesley Said all come into the team, while Kevin Theophile-Catherine, Tiemoune Bakayoko and Jonathan Pitroipa miss out.
Lille manager Rene Girard has made one change to the side that beat Saint-Etienne last weekend.
Soualiho Meite has been replaced by Florent Balmont is midfield, while Salomon Kalou starts up front despite being recently linked with a move to Arsenal.
Rennes: Costil, Danze, Armand, Kana-Biyik, Moreira, Makoun, Feret, Pajot, Erding, Oliveira, Said
Lille: Enyeama, Beria, Kjaer, Basa, Souare, Mavuba, Gueye, Balmont, Martin, Rodelin, Kalou
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