Anderlecht secured a comfortable 2-0 win against 10-man Galatasaray thanks to a brace from defender Chancel Mbemba Mangulu but both sides have been eliminated after Arsenal beat Borussia Dortmund in the other Group D fixture.
Aleksandar Mitrovic should have put the hosts ahead early on but failed to connect with Frank Acheampong's left-wing cross with the goal at his mercy.
Anthony Vanden Borre had his appeals for a penalty dismissed by Croatian referee Ivan Bebek, before Steven Defour saw his mishit volley strike both posts after rolling agonisingly across the goal line.
Anderlecht took the lead just before half time when defender Mbemba headed home from six yards out after Mitrovic's smart flick-on.
Bebek was again the subject of Anderlecht's anger as he pulled play back for a foul on Tarik Camdal when winger Ibrahima Conte was through on goal on 55 minutes.
Galatasaray's first real chance of note came just before the hour mark when Osman Tarik Camdal's powerful free kick was beaten away by Silvio Proto.
Hamit Altintop's ball over the top then found Burak Yilmaz, who sent a lobbed effort against the bar as Cesare Prandelli's side suddenly came to life.
However, their hopes of finding a leveller were extinguished on 83 minutes when Selcuk Inan was dismissed for a second bookable offence.
With a man advantage, Anderlecht wrapped up the win when Mbemba reacted quickest to fire home the lose ball after Fernando Muslera had spilled a shot.
The victory means that the Belgian side will drop into the Europa League as Galatasaray finish bottom of Group D.
Joe Sharratt
