Tottenham Hotspur and Anderlecht have made three changes apiece for their Europa League Group J clash at White Hart Lane.
Kieran Trippier, Ben Davies and Ryan Mason come into the side at the expense of Mousa Dembele, Kyle Walker and Danny Rose, while Andros Townsend misses out after clashing with Spurs fitness coach Nathan Gardiner.
Besnik Hasi's visiting charges, meanwhile, see Fabrice N'Sakala, Steven Defour and Frank Acheampong take places in the starting XI ahead of Ibrahima Conte, Imoh Ezekiel and Ivan Obradovic.
Spurs are third in a tight group with two points separating all four teams at the halfway stage.
Tottenham Hotspur: Lloris, Trippier, Alderweireld, Vertonghen, Davies, Alli, Dier, Lamela, Mason, Eriksen, Kane
Subs: Vorm, Fazio, Wimmer, Carroll, Dembele, Onomah, Son
Anderlecht: Proto, Deschacht, Kara, Najar, Defour, Aceampong, N'Sakala, Gillet, Tielemans, Dendoncker, Okaka
Subs: Roef, Nuytinck, Sylla, Conte, Ezekiel, Suarez, Lukebakio
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Giuseppe Labellarte
