Sir Alex Ferguson has made four changes to his starting lineup for this afternoon's trip to Wolverhampton Wanderers.
Ryan Giggs and Ashley Young are among those to drop out of the team, while Paul Scholes and Antonio Valencia have been handed starting roles.
Hosting Wolves will begin the encounter with Kevin Doyle and Steven Fletcher in attack.
Wolves: Hennessey; Zubar, Stearman, Bassong, Ward; Foley, Edwards, Davis, Jarvis; Doyle, Fletcher
Man United: De Gea; Rafael, Ferdinand, Evans, Evra; Valencia, Carrick, Scholes, Welbeck; Hernandez, Rooney