England head coach Stuart Lancaster has named uncapped duo Tom Johnson and Joe Marler in the national side's squad for their first Test match against South Africa.
Exeter flanker Johnson and Harlequins prop Marler have been implemented into the team as replacements for Tom Croft and Alex Corbisiero.
Lee Dickson has been dropped in favour of Ben Youngs at scrum-half for Saturday's clash, while Ben Foden has been moved to the wing to allow Mike Brown to play at full-back.
Quins captain and Aviva Premiership Player of the Year Chris Robshaw will captain the side for the three-match series.
England team: Mike Brown, Chris Ashton, Manu Tuilagi, Brad Barritt, Ben Foden, Owen Farrell, Ben Youngs, Joe Marler, Dylan Hartley, Dan Cole, Mouritz Botha, Geoff Parling, Tom Johnson, Chris Robshaw (c), Ben Morgan