Ireland head coach Declan Kidney has handed fly-half duties to Ronan O'Gara for the team's clash with Italy on Sunday.
O'Gara is joined in the half-backs by Munster teammate Conor Murray in the only changes to the Irish side that beat Australia 15-6 two weeks ago.
Ireland: Rob Kearney, Tommy Bowe, Brian O'Driscoll (c), Gordon D'Arcy, Keith Earls, Ronan O'Gara, Conor Murray, Jamie Heaslip, Sean O'Brien, Stephen Ferris, Paul O'Connell, Donncha O'Callaghan, Mike Ross, Rory Best, Cian Healy
Replacements: Sean Cronin, Tom Court, Donnacha Ryan, Denis Leamy, Eoin Reddan, Jonathan Sexton, Andrew Trimble