The 60-year-old was in his second spell as boss, having managed the club between 1995 and 2000.
Hearts drew with Rangers 1-1 in their opening game of the Scottish Premier League season, although they were beaten 1-0 by Dundee United at the weekend.
The Hearts squad were told of Jefferies's departure this afternoon.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Celtic | 25 | 21 | 3 | 1 | 73 | 12 | 61 | 66 |
| 2 | RangersRangers | 25 | 16 | 5 | 4 | 51 | 19 | 32 | 53 |
| 3 | Dundee UnitedDundee Utd | 25 | 10 | 7 | 8 | 32 | 28 | 4 | 37 |
| 4 | Aberdeen | 25 | 10 | 5 | 10 | 32 | 38 | -6 | 35 |
| 5 | Hibernian | 25 | 8 | 9 | 8 | 37 | 37 | 0 | 33 |
| 6 | Motherwell | 25 | 9 | 4 | 12 | 30 | 42 | -12 | 31 |
| 7 | Hearts | 25 | 8 | 6 | 11 | 34 | 33 | 1 | 30 |
| 8 | St Mirren | 25 | 9 | 3 | 13 | 30 | 39 | -9 | 30 |
| 9 | Kilmarnock | 25 | 7 | 7 | 11 | 28 | 40 | -12 | 28 |
| 10 | Dundee | 25 | 7 | 6 | 12 | 37 | 53 | -16 | 27 |
| 11 | Ross County | 25 | 6 | 8 | 11 | 24 | 47 | -23 | 26 |
| 12 | St Johnstone | 25 | 6 | 3 | 16 | 28 | 48 | -20 | 21 |
| > Scottish Premiership Full Table | |||||||||
