Spain striker Alvaro Negredo has been handed his first start of the tournament for tonight's Euro 2012 semi-final against Portugal.
The centre-forward has replaced Fernando Torres, while Cesc Fabregas has also been forced to settle for a place on the bench.
For Portugal, Hugo Almeida will start in attack in place of the injured Helder Postiga.
Spain: Casillas; Arbeloa, Ramos, Pique, Alba; Busquets, Alonso, Xavi, Iniesta, Silva; Negredo
Portugal: Patricio; Pereira, Pepe, Alves, Coentrao; Veloso, Moutinho, Meireles, Nani; Almeida, Ronaldo