Bologna vs. Genoa (Tuesday, 5.30pm)
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Having seen their fine start brought to a shuddering halt at the weekend, Bologna welcome struggling Genoa to Stadio Renato Dall'Ara on Tuesday.
Crushed 6-1 by champions Inter Milan, the Rossoblu suffered a first defeat of their Serie A campaign, while their midweek visitors fell to a third defeat in four.
We say: Bologna 2-2 Genoa
Genoa just cannot keep the back door shut, so Bologna are almost certain to score at some stage - particularly given some good options behind the central striker.
However, this battle of the Rossoblu is set to end with the spoils shared, as the Emilian hosts may still have their heads spinning from a heavy defeat just three days previously.
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Atalanta vs. Sassuolo (Tuesday, 7.45pm)
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After important late goals saved them at home and in Europe during the past week, Atalanta BC welcome Sassuolo to the Gewiss Stadium on Tuesday evening.
The Bergamaschi have been indebted to strikes in the final 15 minutes in each of their last two outings, and now they face opponents who are struggling to maintain momentum under new leadership.
We say: Atalanta BC 2-1 Sassuolo
The odds are stacked against Sassuolo on Tuesday, as Atalanta are getting closer to their irresistible peak and can generally score from all departments - no matter what their starting XI.
Because the visitors have suffered an unusual lack of cutting edge of late, they will be outscored by their hosts, who can then prepare for a major clash at San Siro.
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Fiorentina vs. Inter Milan (Tuesday, 7.45pm)
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Two of the form sides in Serie A clash at Stadio Artemio Franchi on Tuesday, as champions Inter Milan visit Fiorentina.
While the Nerazzurri crushed Bologna 6-1 at the weekend, their midweek hosts were posting a third straight win, which lifts them into the top five of the early-season standings.
We say: Fiorentina 1-2 Inter Milan
Inter have reigned supreme over Fiorentina in recent months and can continue to build another Serie A winning streak with victory over their Tuscan counterparts on Tuesday.
Even if the Nerazzurri rotate their considerable resources, a lethal forward line can surely slice through the attack-minded Viola on several occasions - and they rarely fail to capitalise.