Juventus vs. Venezia (Sunday, 11.30am)
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Seeking to snap their eight-game losing streak and begin a late push from the drop zone, Venezia take a trip to the Allianz Stadium to square off with Juventus on Sunday.
Massimiliano Allegri's side, on the other hand, are currently on a four-game unbeaten run and will head into the game seeking to to keep their slim title hopes alive.
We say: Juventus 2-0 Venezia
While Venezia will be desperate to keep their survival hopes alive, next up is a rampant Juventus side who are mathematically in contention for the Scudetto. Given the gulf in class and quality between the sides, and their contrasting form, we are tipping Juventus to come away with all three points unscathed.
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Empoli vs. Torino (Sunday, 2.00pm)
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After finally ending their search for a first win of 2022 in spectacular style, Empoli welcome mid-table counterparts Torino to Tuscany on Sunday afternoon.
The teams meet at Stadio Carlo Castellani with the hosts now seeking back-to-back home victories, while their visitors aim to recover from letting two points slip in midweek.
We say: Empoli 2-2 Torino
Even including their heroics last time out, Empoli have won just four times at home since promotion back to the top flight last summer, and are more likely to draw according to recent trends.
In 2022, the Azzurri have finished seven league games all-square - only Genoa have done so more since the turn of the year - and Torino have drawn each of their last three too.
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AC Milan vs. Fiorentina (Sunday, 2.00pm)
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Aiming to pull five points clear in the race for the Scudetto, AC Milan host a Fiorentina side keenly pursuing European qualification on Sunday afternoon.
Playing just before city rivals Inter, the Rossoneri meet their fellow beaten Coppa Italia semi-finalists at San Siro, with a first Serie A title since 2011 almost within touching distance.
We say: AC Milan 1-0 Fiorentina
Milan and Fiorentina have not drawn a Serie A fixture at San Siro since 2014, but this weekend's encounter could be a close-run affair, given the stakes for either side.
An aberration against Inter aside, the Rossoneri have been defensively resolute for the past few months, so they can keep their visitors at arm's length and rely on their established ability to nick points by the slimmest of margins.
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Udinese vs. Inter Milan (Sunday, 5.00pm)
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After a calamitous defeat in midweek, reigning champions Inter Milan aim to keep their title defence alive by taking maximum points against mid-table Udinese on Sunday.
Now running out of games to surpass city rivals Milan at the Serie A summit, Inter returned empty-handed from Bologna on Wednesday, and now face opponents who were recently on the right side of another unexpected result.
We say: Udinese 1-2 Inter Milan
Having lost just four times at home all season, Udinese are a force to be reckoned with at the Dacia Arena, but Inter arrive with the bit between their teeth and are sure to leave nothing in reserve following Wednesday's events.
The hosts are set to score at least once, given their front-line fluency of late, but the champions will not make the same mistakes again and should be able to grind out a precious victory.
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Roma vs. Bologna (Sunday, 7.45pm)
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Still seeking points to confirm their return to Europe next season, Roma welcome giant-killers Bologna to Stadio Olimpico on Sunday evening, after the visitors toppled Inter in midweek.
Perhaps playing a crucial part in the Scudetto's destiny, the Rossoblu were 2-1 winners on Wednesday, while Jose Mourinho's side followed league defeat to the same opponents with a draw at Leicester City, in the first leg of their Europa Conference League semi-final.
We say: Roma 2-1 Bologna
Certainly a match for Calcio's best sides on their day, Bologna will be no pushovers in Sunday's late kick-off, but they may still find their unbeaten streak halted by Roma.
The hosts have so often found a way to steal points in the final minutes and can battle past visitors who have toiled on their travels of late.