Bologna vs. Torino (Sunday, 11.30am)
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Following last week's win over the champions, Torino aim to build on that success when they visit Bologna on Sunday afternoon, at Stadio Renato Dall'Ara.
Having posted three consecutive victories since losing the Turin derby, the Granata are enjoying their most fruitful spell of the season; their hosts, meanwhile, beat Monza last time out in Serie A and now sit comfortably in mid-table.
We say: Bologna 1-1 Torino
Both teams have scored at a rate of around one goal per game in Serie A this season, and under Ivan Juric, Torino tend to keep things tight. Therefore, a low-scoring draw could be on the cards at Dall'Ara, which would see either side extend their unbeaten run.
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Sampdoria vs. Fiorentina (Sunday, 2.00pm)
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Three straight wins have helped Fiorentina stop the rot in Serie A and seal progress in Europe, and they attempt to maintain that momentum on Sunday, when they visit struggling Sampdoria.
The teams meet at Stadio Luigi Ferraris, with Samp sitting 18th in the standings and their visitors five places above them.
We say: Sampdoria 1-2 Fiorentina
Both sides have found the net in every one of the clubs' last 13 Serie A meetings since 2015, in a fixture which averages 3.6 goals per game. Neither have been prolific this term, but with Fiorentina finally finding their shooting boots, the visitors can head back to Tuscany with three points in their pocket.
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Monza vs. Hellas Verona (Sunday, 2.00pm)
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Monza and Hellas Verona will both be looking to end significant losing runs when they meet in Serie A on Saturday.
Monza have lost three successive matches, while Verona are only off the foot of the table by virtue of goals scored having been defeated seven times in a row.
We say: Monza 2-1 Hellas Verona
With Verona missing several key players through injury and suspension, we can envisage Monza returning to winning ways and extending the visitors' sizable losing streak.
Having finished in the top half in each of the last three seasons, Verona appear to be in serious danger of returning to Serie B unless they can make significant positive changes after the World Cup break.
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Roma vs. Lazio (Sunday, 5.00pm)
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Separated by just one point and one place in the Serie A standings, eternal rivals Roma and Lazio clash at Stadio Olimpico, in Sunday's Derby della Capitale.
Having sealed progress in Europe this week, the Giallorossi also hold the upper hand after 12 rounds of the Italian top flight, while their Biancocelesti counterparts have lost twice in the last few days; ending a fantastic run of form.
We say: Roma 2-1 Lazio
The Derby della Capitale has seen more red cards than any other fixture in Serie A since the turn of the century, yet there has been just one dismissal in the six most recent meetings between Lazio and Roma. With so much at stake, a more ill-tempered encounter could break out, which might suit the Giallorossi more as Mourinho's pragmatism trumps 'Sarrisimo' again.
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Juventus vs. Inter Milan (Sunday, 7.45pm)
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With both clubs lagging behind in the Serie A title race, old rivals Juventus and Inter Milan battle it out for three precious points in Turin, as they contest Sunday's Derby d'Italia.
Not only did Inter beat their hosts to victory in last season's Coppa Italia final and the Supercoppa Italiana, but they are also two points ahead of an ailing Old Lady before the teams reconvene this weekend.
We say: Juventus 1-0 Inter Milan
Both sides have finally found produced some consistent results in Serie A, but find themselves off the pace at the summit of the standings. Juve have become accustomed to snatching the odd goal and grinding out ugly wins, and they can pull that trick off again versus Inter, with several key players returning to the squad just in time for the Derby d'Italia.