Roma vs. Inter Milan (Sunday, 11.30am)
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Scudetto rivals Roma and Inter Milan clash at Stadio Olimpico on Sunday, with just three points and two places separating them in the table.
Curiously, both sides have played Crotone and Sampdoria since the winter break - with Roma taking maximum points and Inter collecting just three after a shock defeat in Genoa.
We say: Roma 2-2 Inter Milan
This box-office lunchtime showdown has all the makings of a classic encounter, with much already at stake before Serie A has even reached its halfway point.
Roma's scintillating attacking patterns could unsettle an Inter defence that has improved but conceded twice in both of their last two games - but Lukaku's return to the starting lineup can inspire the dogged visitors to fight fire with fire at the Olimpico.
Our tipster partners are predicting an away win.
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Parma vs. Lazio (Sunday, 2.00pm)
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Fast sinking Parma welcome an old acquaintance back to the Tardini dugout on Sunday, as eighth-placed Lazio visit a home side stuck in the Serie A relegation zone.
Roberto D'Aversa took charge for a second time earlier this week and must first pit his wits against the Biancocelesti's highly-rated head coach Simone Inzaghi.
We say: Parma 0-1 Lazio
Parma just cannot buy a goal at the moment and even a change in management may not be able to shake up a shot-shy strikeforce against Lazio.
Even if the Biancocelesti are not at full gas on Sunday, the penalty area prowess of Immobile and Caicedo can steer them to a second successive league win - continuing their recent dominance over the struggling Gialloblu.
Our tipster partners are predicting an away win.
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Udinese vs. Napoli (Sunday, 2.00pm)
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Following a catastrophic collapse in midweek, Napoli travel north to meet Udinese on Sunday, seeking to recover from a run of three defeats in five.
Their Friulian hosts have slipped down the Serie A standings of late - also with no wins in five - and are now just four points above the drop zone.
We say: Udinese 1-2 Napoli
On Sunday, Napoli will undoubtedly be fired up by both their profligacy against Spezia and their outspoken coach's angry response.
This is a particularly good time to take on an often tricky Udinese outfit too, as injuries and waning form make the Friulani a less likely source of a second successive upset for the Neapolitan side.
Our tipster partners are predicting an away win.
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Hellas Verona vs. Crotone (Sunday, 2.00pm)
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Hellas Verona take on Crotone in Serie A on Sunday with the visitors looking to move off the foot of the table with a victory.
Verona, meanwhile, are currently occupying a top-half position once again, having impressively finished ninth in their first season back in Serie A last season.
We say: Hellas Verona 2-1 Crotone
With Verona in good form this season, we can envisage them getting back to winning ways against a leaky Crotone outfit.
The visitors have shown their attacking potency in recent matches, though, so it would be little surprise to see them scoring past a strong Verona defence.
Our tipster partners are predicting a home win.
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Fiorentina vs. Cagliari (Sunday, 5.00pm)
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Fiorentina entertain Cagliari in Serie A on Sunday with the two sides separated by a solitary point in the table.
The visitors are in desperate need of a positive result, having failed to win any of their last nine league matches.
We say: Fiorentina 2-1 Cagliari
With Cagliari missing several first-team players due to a combination of injury, illness and suspension, we can envisage a home victory for Fiorentina.
Prandelli's side rarely do things the easy way, though, with Joao Pedro likely to be a thorn in their side throughout the match.
Our tipster partners are predicting a home win.
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Juventus vs. Sassuolo (Sunday, 7.45pm)
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After a crucial victory at San Siro in midweek, Juventus welcome close challengers Sassuolo to Turin on Sunday, determined to keep pressure on the league-leading Milan clubs.
Roberto De Zerbi's overachieving visitors have started the new year in a mixed manner following a heavy opening loss with Wednesday's win over Genoa.
We say: Juventus 2-1 Sassuolo
Though they enjoyed some fortune against absence-hit Milan in midweek, Juve's win at San Siro had a potentially season-defining feel to it.
Now, they must put Sassuolo to the sword - another difficult proposition - as their next generation start to settle in to life in the Bianconeri goldfish bowl.
Even if the visitors break through their defence, Juventus can rely on an impressively deep bench to bail them out and seal a third straight victory to start the year.
Our tipster partners are predicting a home win.
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Spezia vs. Sampdoria (Monday, 7.45pm)
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Riding high after spectacular comeback wins against Serie A's big boys, both Spezia and Sampdoria meet on Monday night aiming to build on unexpected midweek successes.
Vincenzo Italiano's side pulled off an incredible triumph over Napoli on Wednesday, while resolute Samp downed Inter Milan at Marassi.
We say: Spezia 1-1 Sampdoria
With confidence high in both camps after against-the-odds wins, the prospects of a closely-fought encounter to close Serie A's 17th round are particularly high.
Goals have come with great frequency - at either end - when these two teams have taken the field in recent weeks, so inconsistent Sampdoria will have to content themselves with a score draw on Monday night.
Our tipster partners are predicting a double chance bet on a draw or an away win.