New signing Erik Pieters has been handed a home debut by boss Mark Hughes in their final pre-season friendly against Genoa.
The Dutchman has been signed from PSV Eindhoven, and he will start at left-back against the Serie A outfit.
There is also a start for Peter Crouch in attack, with former Barcelona defender Marc Muniesa taking a place on the bench.
Former AC Milan striker Alberto Gilardino has been named in Genoa's lineup by head coach Fabio Liverani.
Stoke City: Begovic, Cameron, Shawcross, Huth, Pieters, Palacios, Nzonzi, Adam, Walters, Etherington, Crouch
Genoa: Perin, Biondini, Lodi, Gilardino, Antonelli, Cofie, Santana, Vrsaljko, Manfredini, Portanova, Bertolacci
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