Zenit St Petersburg will welcome Real Betis to the Gazprom Arena on Thursday for the first leg of their Europa League knockout tie.
The reigning Russian Premier League champions enter the competition after dropping down from the Champions League, while Manuel Pellegrini's side feature in the playoff round following a second-placed finish in their Europa League group.
Match preview
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Thursday's Europa League contest represents Zenit's first meaningful fixture since a 1-1 league draw against Dynamo Moscow on December 12.
With the Russian Premier League currently on a winter break, Thursday's hosts have spent recent weeks playing in friendlies and competing in the Atlantic Cup - a mid-season tournament for those participating in leagues with long winter breaks.
Sergei Samak's side can take confidence from the fact they won the Atlantic Cup for the second time, but their main focus now turns to two crucial games against Real Betis.
Despite winning once in the Champions League group stage, Zenit competed well in a difficult group that contained Juventus and Chelsea, while their five-point tally was enough to secure them a place in the Europa League last 32.
Zenit will be confident of making the most of home advantage, having won nine of their previous 12 home matches in the Europa League knockout phase.
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Real Betis enter the first leg in a buoyant mood after winning their last two matches in all competitions, including a 4-2 away victory against Levante on Sunday.
Goals from Nabil Fekir, Edgar Gonzalez and William Carvalho gave Los Verdiblancos a three-goal lead before Dani Gomez netted either side of half time to cut the deficit to one, but another Fekir effort ensured that the visitors would take all three points back to Andalusia.
To this point, Real Betis have enjoyed a successful season, with Pellegrini's side one game away from the Copa del Rey final after winning the first leg of their semi-final against Rayo Vallecano, while they currently occupy a position in the top four of La Liga as they look to qualify for the Champions League.
On Thursday, Los Verdiblancos will turn their focus towards European action as they aim to clinch just their second competitive victory over Russian opposition.
Having won their last four away matches in all competitions, Real Betis will head to the Gazprom Stadium full of confidence, with the visitors aiming to pick up a positive result to take back to the Estadio Benito Villamarin.
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Team News
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Zenit St Petersburg will be without the services of Dejan Lovren, who picked up an ankle ligament injury in the Atlantic Cup match against FC Copenhagen.
Stanislav Kritsyuk is also unavailable, having been out with a knee issue since the beginning of November.
Meanwhile, Artem Dzyuba has scored 10 goals this season, and he will have the responsibility of leading the line on Thursday.
As for the visitors, their injury absentees include Claudio Bravo, Martin Montoya and Juan Miranda while Fekir is suspended for the first leg.
As well as Fekir, Sergio Canales could be another big miss for the trip to Russia, with the 30-year-old a doubt for Thursday's encounter after missing his side's last two games following a positive COVID-19 test.
Guido Rodriguez missed Sunday's clash with Levante due to injury, but the Argentina international could return to the lineup to face Zenit on Thursday.
Zenit St Petersburg possible starting lineup:
Kerzhakov; Chistyakov, Barrios, Rakitskiy; Karavaev, Wendel, Kusyaev, Santos; Malcom, Claudinho, Dzyuba
Real Betis possible starting lineup:
Silva; Bellerin, Bartra, Pezzella, Moreno; Rodriguez, Carvalho, Rodri; Ruibal, Juanmi, Iglesias
We say: Zenit St Petersburg 1-1 Real Betis
Although the visitors may be missing a couple of key players, they have proven to be a tough team to beat on their travels this season.
Zenit, meanwhile, may be slightly undercooked due to the lack of competitive football and although they possess home advantage, we think that they may be held to a draw on Thursday.
Top tip
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Zenit St Petersburg win with a probability of 50.24%. A win for Real Betis had a probability of 27.69% and a draw had a probability of 22.1%.
The most likely scoreline for a Zenit St Petersburg win was 2-1 with a probability of 9.35%. The next most likely scorelines for that outcome were 1-0 (6.93%) and 2-0 (6.71%). The likeliest Real Betis win was 1-2 (6.73%), while for a drawn scoreline it was 1-1 (9.66%). The actual scoreline of 2-3 was predicted with a 3% likelihood.
