Paulo Dybala and Giorgio Chiellini will start on the bench for Juventus in tonight's game against Frosinone.
Gianluigi Buffon is also rested, while Alex Sandro replaces Patrice Evra at left-back.
Paul Pogba retains his spot in the starting XI, after helping kick-start Juve's campaign with a 2-0 win over Genoa on Sunday.
Roberto Stellone has given the nod to Nicolas Castillo and Daniel Ciofani to spearhead the attack for Frosinone.
Juventus: Neto; Lichtsteiner, Barzagli, Bonucci, Alex Sandro; Sturaro, Lemina, Pogba; Cuadrado, Zaza, Pereyra
Subs: Buffon, Audero, Rugani, Chiellini, Evra, Padoin, Hernanes, Dybala, Favilli
Frosinone: Leali; Ciofani, Diakite, Blanchard, Crivello; Frara, Gori, Chibsah, Soddimo; Ciofani, Castillo
Subs: Zappino, Russo, Verde, Paganini, Dionisi, Tonev, Pavlovic, Sammarco, Gomis, Rosi, Carlini, Bertoncini