Everton vs. West Brom (Saturday, 12.30pm)
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Two teams that suffered contrasting fortunes on the opening weekend of the new Premier League season will face off at Goodison Park on Saturday when Everton host West Bromwich Albion.
Carlo Ancelotti's side kicked off their campaign with an impressive 1-0 win at Tottenham Hotspur, whereas the newly-promoted Baggies were soundly beaten at home to Leicester City.
We say: Everton 2-0 West Bromwich Albion
Everton looked good against an admittedly below-par Tottenham last weekend, and they are only likely to get better once the new signings settle in more.
West Brom, meanwhile, suffered a difficult first taste of life back in the top flight and we do not expect it to get much easier for them at Goodison.
Our tipster partners are predicting under 3.5 goals.
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Leeds vs. Fulham (Saturday, 3.00pm)
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Premier League football returns to Elland Road for the first time in 16 years on Saturday when Leeds United host fellow newly-promoted side Fulham.
Marcelo Bielsa's men made an explosive return to the top fight in a 4-3 defeat to champions Liverpool on the opening weekend, while Fulham were comfortably beaten at home to Arsenal.
We say: Leeds United 2-1 Fulham
In a strange way, Leeds may find matches like these more difficult than the ones against the top clubs this season. Liverpool allowed Leeds space to play in the confidence that they would be able to outscore their visitors, whereas Fulham are unlikely to be so generous.
We still expect the hosts to celebrate top-flight football returning to Elland Road with a victory, but they may find openings more difficult to come by than they did last weekend.
Our tipster partners are predicting under 3.5 goals.
> Click here to read our full preview for this match
Man Utd vs. Crystal Palace (Saturday, 5.30pm)
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Manchester United get their 2020-21 campaign belatedly underway when they welcome Crystal Palace to Old Trafford on Saturday afternoon.
Just over a month after their 2019-20 season finished in the Europa League semi-finals, Ole Gunnar Solskjaer's side are back in competitive action a week later than most teams, including Palace, who began the campaign with a 1-0 win over Southampton.
We say: Manchester United 2-1 Crystal Palace
The hosts are not in the best shape possible heading into this season opener, which is understandable given they have only had a month off.
However, Solskjaer should still be able to name a team strong enough to see off Palace, who are struggling even more with injuries and whose win in the corresponding fixture last season was very much an exception to the rule in the Premier League era.
Our tipster partners are predicting a home win.
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> How Man United could line up against Crystal Palace
> Man United injury, suspension list vs. vs. Palace
Arsenal vs. West Ham (Saturday, 8.00pm)
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Arsenal will be looking to make it back-to-back victories to begin the Premier League campaign when they welcome West Ham United to the Emirates Stadium on Saturday.
The Gunners eased to a 3-0 win over Fulham in their first top-flight fixture of the season, while West Ham were beaten 2-0 by Newcastle United in their home opener.
We say: Arsenal 2-0 West Ham United
The mood around both clubs could not be much more contrasting. Arsenal enter the fixture on a high after kicking off their 2020-21 campaign with back-to-back wins, while West Ham lost to Newcastle in their league opener and have a very tough run of fixtures ahead.
Arsenal have lost their first home game in five of the last nine Premier League campaigns, which includes a defeat against West Ham in 2015-16, but we cannot see past anything other than a routine home win this weekend.
Our tipster partners are predicting under 3.5 goals.
> Click here to read our full preview for this match
> How Arsenal could line up against West Ham United
> Arsenal injury, suspension list vs. West Ham