Real Madrid boss Carlo Ancelotti has revealed that Jude Bellingham and Kylian Mbappe will not be available for Thursday's Copa del Rey quarter-final against Leganes.
Los Blancos will be looking to bounce back from Saturday's surprise defeat against Espanyol when they make the short trip across the city for the last-eight tie.
However, their preparations have been blighted by a number of injury issues, beginning with a hamstring problem that Antonio Rudiger picked up in the loss to Espanyol.
Ancelotti has since confirmed that David Alaba has joined Rudiger on the sidelines after sustaining a muscle injury in training.
Alaba and Rudiger are both expected to be out for around three weeks, leaving Ancelotti with Raul Asencio, Aurelien Tchouameni and Jacobo Ramon as his main central defensive options.
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Real Madrid suffer Bellingham, Mbappe blows
To make matters worse, Ancelotti has also revealed that Bellingham and Mbappe will not be available for the Copa del Rey meeting with Leganes.
Speaking in his pre-match press conference, Ancelotti told reporters: "Bellingham had a bruise from a knock and will not be available. Vinicius Junior has been given an extra day to recover, but will be available.
"Mbappe trained. He has a bruise on his calf. He trained normally, but he won't be available for the game."
Bellingham and Mbappe will now look to shake off those knocks in time for Saturday's derby clash against local rivals Atletico Madrid.
Real Madrid will also be desperate for two of their star players to be fit for next Tuesday's Champions League encounter with Manchester City.
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Who will replace Bellingham and Mbappe?
With Bellingham ruled out, Brahim Diaz is likely to get the chance to operate in the number 10 role for the Copa del Rey fixture.
Meanwhile, Endrick is poised to replace Mbappe as Real Madrid's main striker, with the Brazilian looking for more cup success after netting a brace in the previous round.
Arda Guler could also be given the opportunity to start if Ancelotti decides to use Rodrygo from the bench in a bid to keep his squad fresh in a busy period.
At the opposite end of the pitch, Andriy Lunin will feature between the posts, with Thibaut Courtois set to be rested for the quarter-final tie.
Real Madrid are still without long-term absentees Dani Carvajal and Eder Militao, while Eduardo Camavinga will not be ready despite making progress in his injury recovery.
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