Manchester United could be without as many as 10 first-team players for Saturday's Premier League clash with Bournemouth at the Vitality Stadium.

The Red Devils have confirmed that Raphael Varane is ruled out for a few weeks with a muscle injury, while Jonny Evans is sidelined with a "shorter-term muscle issue" and both players join Lisandro Martinez (calf), Victor Lindelof (hamstring), Luke Shaw (muscle), Tyrell Malacia (knee) and Anthony Martial (groin) in the treatment room.

Scott McTominay picked up an unspecified issue during the 4-3 defeat at Chelsea and subsequently missed last weekend's 2-2 draw with Liverpool, a game in which Marcus Rashford was forced off in the second half due to a minor injury; both players will be assessed ahead of kickoff, as will Sofyan Amrabat who was not spotted in training on Thursday.

Man United are light in the defensive department, so Erik ten Hag is set to stick with 19-year-old Willy Kambwala and Harry Maguire at centre-back as Aaron Wan-Bissaka and Diogo Dalot operate as full-backs.

Kobbie Mainoo, who scored his first goal at Old Trafford last weekend, is expected to continue in centre-midfield alongside Casemiro, with captain Bruno Fernandes keeping his place in the number 10 role; both Mason Mount and Christian Eriksen are set to provide cover as substitutes once again.

If Rashford is not deemed fit to start, then Antony would be expected to deputise on the right flank with Alejandro Garnacho moving over to the left, while Rasmus Hojlund will lead the line and is looking to end a four-game goal drought.

Manchester United possible starting lineup: Onana; Dalot, Kambwala, Maguire, Wan-Bissaka; Casemiro, Mainoo; Antony, Fernandes, Garnacho; Hojlund