Barcelona will be missing five players through injury for Wednesday's Champions League clash with Inter Milan at Camp Nou.

Frenkie de Jong made his return from injury in Sunday's 1-0 win over Celta Vigo in La Liga, but Andreas Christensen, Hector Bellerin, Ronald Araujo, Memphis Depay and Jules Kounde remain on the sidelines.

Franck Kessie was also expected to miss out with a thigh problem, but the Ivory Coast international has returned to the squad.

Head coach Xavi will make changes from the side that started against Celta, with Ansu Fati set to return in a forward area, while Ousmane Dembele will also come back into the XI.

Defensive issues have caused Xavi a problem when it comes to selecting his side, but it would not be a surprise to see Sergi Roberto back in the team at right-back on Wednesday night.

Marcos Alonso could then line up on the opposite side, with Gerard Pique and Eric Garcia set to feature as the two central defenders for the key European encounter.

De Jong's return has given Xavi another option in midfield, but Gavi, Pedri and Sergio Busquets are again expected to play as the central three in a 4-3-3 formation.

Robert Lewandowski has failed to score in his last two appearances for Barcelona, but the Poland international will again lead their line against Inter here.

Xavi might have considered played a back three in this match, but the recent injury problems makes that unlikely, with Christensen, Kounde and Araujo all out.

Barcelona possible starting lineup: Ter Stegen; Roberto, Pique, E Garcia, Alonso; Gavi, Busquets, Pedri; Dembele, Lewandowski, Fati