Barnsley vs. Exeter (Saturday, 3.00pm)
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Barnsley play host to Exeter City on Saturday afternoon with the opportunity to maintain their push for an automatic promotion spot in League One.
At a time when the Tykes sit in fifth position in the standings, the visitors are down in 19th place despite their recent upturn in fortunes.
We say: Barnsley 2-1 Exeter City
Exeter's success at Bristol Rovers can only have lifted spirits ahead of another away fixture, yet they are facing one of the form teams in the division. A competitive encounter may play out, yet we cannot back against Barnsley running out victors come the full-time whistle.
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Blackpool vs. Charlton (Saturday, 3.00pm)
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Looking to extend their unbeaten run in the league, promotion-chasing Blackpool will welcome managerless Charlton Athletic to Bloomfield Road on Saturday afternoon in League One.
The Seasiders were narrow victors at Bristol Rovers in their last fixture, while the Addicks' loss at home to Northampton Town resulted in a change in the dugout.
We say: Blackpool 3-1 Charlton Athletic
Blackpool have been formidable at Bloomfield Road this term, and we see no reason why that trend will not continue against a managerless Charlton on Saturday.
The Addicks are sliding towards an unlikely relegation scrap, and we cannot imagine them earning anything from their trip to the seaside this weekend.
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Bristol Rovers vs. Oxford Utd (Saturday, 3.00pm)
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Aiming to end a four-game losing run, Bristol Rovers will welcome Oxford United to the Memorial Stadium for a crucial League One clash on Saturday afternoon.
The Pirates' poor form continued against Exeter City last time out, while Oxford suffered a rare home defeat at the hands of Yorkshire outfit Barnsley.
We say: Bristol Rovers 1-2 Oxford United
Bristol Rovers are enduring a wretched run of form but have the opportunity to put things right quickly this weekend, although the visit of Oxford will be a tough assignment.
The U's need a win to keep the playoff-chasing pack at arm's length, and we feel that Des Buckingham's men will be able to secure three points on Saturday.
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Cambridge vs. Burton Albion (Saturday, 3.00pm)
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Looking to earn maximum points following a draw last time out, Cambridge United will host Burton Albion at the Cledara Abbey Stadium on Saturday afternoon in League One.
The U's have endured a mixed start to the calendar year across all competitions, while the Brewers ended a worrying winless run in their last fixture to ease pressure on their players.
We say: Cambridge United 1-0 Burton Albion
Cambridge have returned to a consistency of performance in recent matches and will be confident of collecting maximum points against Burton in this one.
The Brewers were deserved winners over Charlton but have lost their last three away games, and we believe that trend will continue at the Abbey Stadium on Saturday.
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Carlisle vs. Bolton (Saturday, 3.00pm)
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Two teams fighting at opposite ends of the League One table will square off at Brunton Park on Saturday, as Carlisle United welcome Bolton Wanderers.
The hosts sit 10 points adrift of safety in 23rd spot, while their visitors will bid to climb back into the automatic promotion spots at the weekend.
We say: Carlisle United 0-2 Bolton Wanderers
Carlisle United will be desperate to complete the double over Bolton Wanderers after their shock win in October, and given their need for points in the fight for survival, but we see them being outclassed by Evatt's side who have their sights set on automatic promotion and quality in abundance throughout their squad.
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Derby vs. Cheltenham (Saturday, 3.00pm)
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Derby County will welcome Cheltenham Town to Pride Park on Saturday for a game of major importance at both ends of the League One table.
A disappointing midweek defeat left the hosts two points outside of the automatic promotion spot, while their visitors currently sit 22nd and seven points adrift of safety.
We say: Derby County 2-1 Cheltenham Town
Keen to bounce back to winning ways against a resilient Cheltenham Town side who are fighting for their third-tier status, Derby County face a difficult test on Saturday but should have the quality to come out on top at Pride Park.
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Lincoln vs. Peterborough (Saturday, 3.00pm)
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Aiming to strengthen their position in the top two of the League One table, Peterborough United will travel to take on Lincoln City on Saturday.
The visitors have moved into the automatic promotion spots with three straight victories, while their hosts sit 12th in the midst of a dip in form.
We say: Lincoln City 0-2 Peterborough United
Despite their growing winless run, Lincoln City do head into the weekend on the back of a pair of more pleasing results and will aim to clip the wings of a dangerous Peterborough side as they did to Derby last time out.
We see the visitors being too strong however, even without Poku, and back them to take all three points back to Cambridgeshire in their promotion bid.
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Northampton vs. Shrewsbury (Saturday, 3.00pm)
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Aiming to further boost their outside playoff chances in the midst of a fine run of form, Northampton Town will welcome Shrewsbury Town to Sixfields on Saturday.
A four-match unbeaten streak has seen the hosts move within nine points of the top six in the League One table, while their visitors sit 20th with just a four-point lead over the bottom four under the new management of Paul Hurst.
We say: Northampton Town 2-0 Shrewsbury Town
The appointment of Hurst may have a positive impact on the Shrewsbury Town camp as they aim to emerge from a rut, but they meet a Northampton Town team who are full of momentum, and we can only envisage the Cobblers adding to their hot streak with another home victory at the weekend.
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Port Vale vs. Portsmouth (Saturday, 3.00pm)
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Portsmouth will attempt to claim a second straight victory when they travel to Vale Park for Saturday's clash with Port Vale.
The hosts are currently sitting in 18th place, while the visitors are one point clear at the top of the League One table.
We say: Port Vale 1-2 Portsmouth
After Portsmouth got their promotion bid back on track last weekend, we think they will record a second straight victory this weekend, especially as they have won two of their last three matches against Port Vale.
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Reading vs. Leyton Orient (Saturday, 3.00pm)
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Leyton Orient will have the chance to claim a fourth consecutive victory when they travel to Berkshire for Saturday's League One clash with Reading.
Meanwhile, the Royals will be targeting a second straight win after edging out Derby County in their midweek outing.
We say: Reading 2-2 Leyton Orient
Although Leyton Orient will be targeting a fourth straight win, we think they may have to settle for a point against a Reading side that has proven to be a tough team to beat on home turf, having avoided defeat in each of their last four home matches.
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Wigan vs. Stevenage (Saturday, 3.00pm)
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Wigan Athletic will try to extend their unbeaten league run to six matches when they welcome Stevenage to the DW Stadium on Saturday.
The Latics, who have had eight points deducted this season, currently occupy 11th place in the League One table, while the visitors are in seventh position and three points adrift of the playoffs.
We say: Wigan Athletic 2-1 Stevenage
Playoff-chasing Stevenage will be targeting a second straight victory as they look to close the three-point gap to the top six.
However, we think the visitors could be in for a disappointing afternoon, as we believe Wigan will claim a narrow win to record a fourth consecutive home victory.
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Wycombe vs. Fleetwood (Saturday, 3.00pm)
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Wycombe Wanderers will want to bounce back from a midweek defeat when they welcome Fleetwood Town to Adams Park on Saturday.
The visitors, who are currently propping up the League One table, will be desperate to end their five-game losing run.
We say: Wycombe Wanderers 2-0 Fleetwood Town
Wycombe may have found wins hard to come by in recent times, but Saturday's contest represents a chance to claim three crucial points in their battle to remain in the third tier.
We think the hosts will do enough to get the better of their opponents, who will be low on confidence following five consecutive defeats.