RB Leipzig vs. VfL Bochum (Saturday, 2.30pm)
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RB Leipzig will be aiming to return to winning ways when they host VfL Bochum in the Bundesliga on Saturday.
The visitors, meanwhile, finally ended their losing streak after claiming a 1-1 draw against FC Koln prior to the international break.
We say: RB Leipzig 2-0 VfL Bochum
Bochum should be better organised and more motivated in Letsch's first game in charge of them, but we are struggling to see beyond a comfortable home win.
After an unconvincing start to the campaign, Leipzig know that they need to start winning more matches sooner rather than later, and are unlikely to pass up a golden opportunity on Saturday.
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Freiburg vs. Mainz 05 (Saturday, 2.30pm)
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Mainz 05 travel to Stade Europa-Park on Saturday to face SC Freiburg in the Bundesliga. Freiburg have started the season strongly, sitting in the Champions League places and ahead of defending champions Bayern Munich.
For Mainz, their indifferent form sees them sitting in eighth, but a win here would see them go level on points with Freiburg.
We say: Freiburg 2-1 Mainz 05
Just three points separate the two sides, but recent form and home advantage might just be the decisive factor here. Freiburg come into the game on the back of three clean sheets in all competitions, whereas Mainz's recent form has been slightly more questionable.
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FC Koln vs. Dortmund (Saturday, 2.30pm)
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Borussia Dortmund will be hoping to move top of the Bundesliga when they visit FC Koln on Saturday.
The hosts, meanwhile, will be hoping to return to winning ways having only won one of their last six league games.
We say: FC Koln 1-2 Borussia Dortmund
Koln have a real opportunity to pounce on Dortmund's mounting injury crisis, with the visitors likely to rely on the return of Malen and Adeyemi to inject fresh life into them.
While it would not be a surprise to see the hosts claim a positive result, we can envisage BVB snatching a tight victory and remain at least three points in front of Bayern in the table ahead of next weekend's meeting at Westfalenstadion.
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Frankfurt vs. Union Berlin (Saturday, 2.30pm)
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High-flying Union Berlin will be looking to maintain their position at the top of the Bundesliga table when they travel to Deutsche Bank Park to face Eintracht Frankfurt on Saturday.
While the visitors are yet to lose in the top flight this season, the hosts are seeking to claim their fourth league victory in five matches.
We say: Eintracht Frankfurt 2-2 Union Berlin
An intriguing contest between two strong Bundesliga sides is set to take place on Saturday, and with at least three goals scored in eight of the last nine meetings between the two clubs, plenty of goalmouth action is to be expected.
However, there is little to separate these two sides and an entertaining score draw could be on the cards at Deutsche Bank Park.
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Wolfsburg vs. Stuttgart (Saturday, 2.30pm)
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Wolfsburg will be looking to claim their first home win of the season when they host Stuttgart in the Bundesliga on Saturday.
The visitors, meanwhile, are still searching for their first victory of the campaign as they make the trip to the Volkswagen Arena.
We say: Wolfsburg 1-1 Stuttgart
Both sides are in similar veins of form and need points, therefore, it would not be surprising to see Kovac and Matarazzo adopt a cautious approach here. We are predicting a score draw.
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Werder Bremen vs. Borussia M'bach (Saturday, 5.30pm)
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Werder Bremen host Borussia Monchengladbach in the Bundesliga this Saturday.
The hosts have performed above expectations after their promotion back to Germany's top flight, while the visitors are looking to make it two consecutive wins here.
We say: Werder Bremen 0-2 Borussia Monchengladbach
Bremen have shown they can upset the bigger teams in the division, already claiming a win over Dortmund and a respectable draw against Leverkusen last time out.
However, Gladbach have made a solid start to their campaign, and Yann Sommer has been in exceptional form. It will be tough to get past the Swiss international.