Juventus duo Martin Caceres and Simone Pepe are both expected to miss the start of the club's Serie A campaign.
The pair both suffered injuries in Saturday's friendly clash with AC Milan, and a statement on the club's official website confirmed the double blow.
"The Uruguayan was this morning [Monday] given an MRI scan and an orthopaedic examination by Professor Quaglia at the Fornaca clinic in Turin. These tests displayed a first-second degree tear of the medial collateral ligament in his left knee," the statement read with regard to Caceres.
"The midfielder [Pepe], assessed by Doctor Ganzit at the city's Medicina dello Sport, underwent an ultrasound scan which showed a first degree tear of the semimembranosus muscle in his left thigh."
Juventus secured the Serie A title last season.