The centre-back pairing, who have started in every Premier League game this season, were both unavailable to play in last night's Champions League fixture against FC Basel due to suspension, meaning that summer signing Victor Lindelof was given his first start for United.
Mourinho told reporters: "If you want to anticipate the next weekend I probably play Bailly and Jones because today they didn't play, because they are fresh, because it makes sense for them to play again, but then two days after we have a League Cup match, so Victor and [Chris] Smalling again."
The omission of Jones and Bailly from the matchday squad did little to help Basel, as the Swiss side fell to a 3-0 defeat at Old Trafford. Despite Paul Pogba being forced off early in the first half with a hamstring problem, substitute Marouane Fellaini put United ahead, before Romelu Lukaku and Marcus Rashford put the game to bed in the second half.
The weekend's match will see Wayne Rooney face his former club for the first time since leaving Manchester in the summer on a free transfer to return to his boyhood club.
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