Napoli will take on Dnipro Dnipropetrovsk in the semi-finals of the Europa League, while Sevilla and Fiorentina will go head to head for a place in the final.
Rafael Benitez's side have escaped their fellow Serie A competitors Fiorentina in the final four, as well as La Liga outfit Sevilla, who are favourites to win the tournament.
Napoli sealed their place in the quarter-finals with a 6-3 aggregate win over Wolfsburg, while Dnipro, who have never won a European trophy, grabbed a 1-0 victory over Club Brugge to advance.
Sevilla will welcome Fiorentina to Spain in the first leg of their semi-final and they managed to edge their way into the final four with a 4-3 aggregate triumph over Zenit St Petersburg.
Fiorentina, who saw off Dynamo Kiev for a place in the semi-finals, have never met Sevilla in European competition.
The first leg of the semi-finals will take place on May 7 and the return leg will take place a week later on May 14.