Manises vs. Getafe (Thursday, 6.00pm)
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Getafe will kick off their Copa del Rey campaign when they travel to the Campo Vicente Martinez Catala for Thursday's Copa del Rey clash with Manises.
The top-flight side are looking to return to winning ways in the first-round clash after drawing each of their last three matches by a 1-1 scoreline.
We say: Manises 1-3 Getafe
Getafe are not a side known for their free-scoring ability, but with the top-flight side set to face a sixth-tier team, we believe that their La Liga quality will help them claim a relatively comfortable victory in Thursday's first-round tie.
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Vic vs. Atletico (Thursday, 6.00pm)
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Atletico Madrid will begin their bid to win their 11th Copa del Rey trophy when they face sixth-tier Vic on Thursday.
The hosts are looking forward to welcoming Diego Simeone's side to the Hipolit Planas Stadium after successfully negotiating a preliminary round tie against Sporting Mahon.
We say: Vic 0-5 Atletico Madrid
Atletico may be low on confidence after losing three of their last five matches in all competitions, but they will have a significant quality advantage over their sixth-tier opponents, and we believe that they will sweep past Vic to sail into the next round.
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San Tirso vs. Espanyol (Thursday, 6.00pm)
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Espanyol travel to A Coruna to face sixth-tier outfit San Tirso in the first round of the Copa del Rey on Thursday evening.
The winners of this contest will advance to the second round where they will be joined by 55 other clubs ahead of next month's draw.
We say: San Tirso 0-3 Espanyol
If Espanyol are to name a strong side with several first-team players, then you would expect the La Liga team to cruise to a comfortable victory. Even if the visitors were to hand some of their B team youngsters a run-out in this one, they should still have enough quality to prevail against their non-league counterparts.
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Gevora vs. Betis (Thursday, 8.00pm)
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Real Betis will travel to the Estadio Francisco de la Hera for Thursday's Copa del Rey clash with sixth-tier Gevora.
Los Verdiblancos will hope the first-round tie is the start of a memorable cup journey as they bid to win the competition for the fourth time in their history.
We say: Gevora 0-5 Real Betis
While Pellegrini is expected to make wholesale changes, Betis will still field a side stacked with considerable quality, who should have far too much firepower for their sixth-tier opponents, which is why we believe the visitors will cruise to a comfortable victory.
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Ontinena vs. Las Palmas (Thursday, 8.00pm)
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Las Palmas make the trip to the autonomous community of Aragon to face sixth-tier outfit Ontinena in the first round of the Copa del Rey on Thursday evening.
The winners of this contest will advance to the second round where they will be joined by 55 other clubs ahead of next month's draw.
We say: Ontinena 0-4 Las Palmas
It is difficult to back against Las Palmas coming out on top in this one, even if they decide to make wholesale changes and call upon some of their B team youngsters. Ontinena will hope to give a good account of themselves, but a comfortable win for the visitors is expected.
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Jove Espanol vs. Real Sociedad (Thursday, 8.00pm)
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La Liga side Real Sociedad will get their Copa del Rey campaign underway when they face fifth-tier Jove Espanol on Thursday.
The hosts have lost their last four matches, while the visitors will head into the first-round tie off the back of a defeat to Osasuna.
We say: Jove Espanol 0-4 Real Sociedad
Real Sociedad have struggled to consistently find the net in La Liga, but we believe a clash against a fifth-tier team will offer them the chance to produce a free-scoring display in what should be a comfortable outing for the top-flight side.
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Ben Knapton
