However, a late red for Chey Dunkley saw Paul Cook's side play the final moments with 10 men and they couldn't hold out.

Town should have been ahead early on, Harry Cornick teeing up Andrew Shinnie, who skied well over from close range.

The hosts, eager to bounce back from a 7-0 hammering at Brentford last weekend, bossed the opening stages, Ryan Tunnicliffe denied by a fine goal-line clearance from Dujon Sterling and then Cornick heading off target.

Wigan went close after 22 minutes when leading scoring Dunkley's header from a deep cross flashed just inches past the post.

Matty Pearson put a great chance over the bar for the hosts from the recalled Luke Berry's free kick while Anthony Pilkington's blast from 25 yards didn't miss by too much either.

Antonee Robinson tried from range, bending wide of the post, before the Latics led after 35 minutes with Sterling sending over a fine cross and Moore rising magnificently to bullet his header beyond James Shea.

Moore then almost made it 2-0, diverting another Sterling cross just wide as Wigan looked to heap more misery on a Luton side looking short of confidence.

After the break, James Collins was denied by the reflexes of Jamie Jones after the keeper's poor clearance went straight at Berry.

The visiting stopper was called upon moments later as Cornick cut the ball back for Tunnicliffe, the midfielder's shot parried to safety.

Wigan had an opportunity to extend their lead, Gavin Massey's snapshot flashing wide, before Charlie Mulgrew fired a presentable free-kick over the bar.

The introduction of Moncur pepped up Town's attacking options, as did former Wigan winger McManaman, the latter trying to equalise against his old club, missing the bottom corner.

However, McManaman did level with three to go, firing home at the second attempt.

Then with Latics' centre-half Dunkley dismissed for a second yellow by hauling back Cornick, Moncur kept his nerve to fire home a first goal of the season and win it for the Hatters.