Manchester City boss Pep Guardiola is set to make a number of changes to his starting side for Saturday's Premier League clash with Watford.

The Citizens are again likely to be without the services of Kyle Walker due to an ankle problem, while Nathan Ake and John Stones both picked up issues during Wednesday's 3-0 win over Brighton & Hove Albion.

Ruben Dias could come in for his first start since recovering from injury, with the Portugal international appearing off the bench against Brighton last time out.

Dias's involvement is likely to depend on whether Stones is passed fit, with the England international's issue believed to be minor, so he should be included in the squad for this contest.

Guardiola will have one eye on next week's Champions League semi-final first leg with Real Madrid, so it would not be a surprise to see a number of changes to the team for this match.

Fernandinho, Raheem Sterling, Jack Grealish, Gabriel Jesus and Oleksandr Zinchenko could all potentially come into the side, with Phil Foden and Bernardo Silva potentially rested from the start.

The Citizens cannot afford to be complacent in the Premier League, though, with Liverpool just a point behind in second, so Guardiola will resist the temptation to change his whole team.

As a result, the likes of Ilkay Gundogan, Kevin De Bruyne and Aymeric Laporte should retain their spots.

Manchester City possible starting lineup: Ederson; Cancelo, Dias, Laporte, Zinchenko; Gundogan, Fernandinho, De Bruyne; Grealish, Sterling, Jesus