Manchester United will be crowned the champions of England for a 20th time if they defeat Aston Villa at Old Trafford tomorrow evening.
The only team that can catch them are rivals Manchester City, who travelled to Tottenham Hotspur this afternoon looking to keep the race alive.
However, their 3-1 defeat has left them 13 points behind United, with five matches left to play.
As a result, any win for United over struggling Villa would see them open up an unassailable 16-point advantage.
A win for Villa would relegate both Reading and Queens Park Rangers to the Championship.