Tottenham Hotspur face Austrian side Wolfsberger on Wednesday evening with one foot already in the Europa League last 16.
Spurs ran out 4-1 winners in last week's first leg and will now be looking to see through the job in a stress-free manner on home soil.
Match preview
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Jose Mourinho has a strong love affair with the Europa League and its UEFA Cup predecessor, and it is a competition he may well be left to rely on to salvage his side's season.
Tottenham were beaten 2-1 by London rivals West Ham United on Sunday to leave them nine points off the top four in the Premier League - a surely insurmountable gap at this stage.
Winning a cup of any sort would make this a successful campaign for Mourinho, though, and he still has two chances to achieve that aim.
The Lilywhites have an EFL Cup final showdown with Manchester City to look forward to in April, while continental success is also a realistic prospect.
The last 16 of the Europa League is now in sight after goals from Son Heung-min, Gareth Bale, Lucas Moura and Carlos Vinicius helped Spurs to a comfortable win last week.
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Wolfsberger, competing in their first major European knockout tie, must now create some history if they are to advance through.
No team in UEFA Cup/ Europa League history has ever overturned a three-goal deficit from the first leg at home during the knockout stages.
Ferdinand Feldhofer's side finished above Feyenoord and CSKA Moscow to reach the last 32 but, positioned fifth in the Austrian Bundesliga, the gulf between themselves and Tottenham told last week.
Tottenham also boast a good record on home soil in Europe, winning each of their last four matches at the Tottenham Hotspur Stadium in the Champions League and Europa League, scoring 16 times and conceding twice.
Tottenham Hotspur Europa League form: LWWDWW
Tottenham Hotspur form (all competitions): LWLLWL
Wolfsberger Europa League form: WLLWWL
Wolfsberger form (all competitions): WWLWLW
Team News
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Giovani Lo Celso and Serge Aurier are Tottenham's only injury absentees for this game, though Joe Rodon will also play no part as he was not registered in Tottenham's European squad.
Son started and scored in the first leg but will surely not be risked here, while the likes of Harry Kane, Pierre-Emile Hojbjerg and Tanguy Ndombele will also be given a breather.
Vinicius is set to return to the starting lineup after coming on as a substitute last week - no Spurs player has scored more Europa League goals this season than the Brazilian, who has netted in each of his last three appearances.
Mourinho also has a decision to make at centre-back, where Japhet Tanganga may be asked to fill in to give Davinson Sanchez and Eric Dier the night off.
As for the visitors, Eliel Peretz has been ruled out and Sven Sprangler is nursing an injury.
However, Mario Leitgeb - who started five of Wolfsberger's six group games - is back in contention after missing the first leg.
Dario Vizinger scored in Sunday's 2-1 league win at Sturm Graz and should lead the line in North London on Wednesday.
Tottenham Hotspur possible starting lineup:
Hart; Doherty, Alderweireld, Tanganga, Davies; Sissoko, Winks; Bale, Alli, Lucas; Vinicius
Wolfsberger possible starting lineup:
Kofler; Novak, Baumgartner, Lochoshvili, Scherzer; Taferner, Liendl, Leitgeb, Wernitznig; Vizinger, Joveljic
We say: Tottenham Hotspur 2-0 Wolfsberger (6-1 on aggregate)
Not since between August 2013 and February 2014 have Spurs won five straight home European matches, though they are strong favourites to achieve that on Wednesday against Austrian minnows Wolfsberger.
The hosts may have lost three of their last four games, and six of their last eight going further back, but they eased to victory in last week's first leg and should do likewise at the Tottenham Hotspur Stadium.
Top tip
Daniel Lewis
Data Analysis
Our analysis of all available data, including recent performances and player stats up until an hour before kickoff, suggested the most likely outcome of this match was a Tottenham Hotspur win with a probability of 53.49%. A win for Wolfsberger had a probability of 25.93% and a draw had a probability of 20.6%.
The most likely scoreline for a Tottenham Hotspur win was 2-1 with a probability of 9.07%. The next most likely scorelines for that outcome were 3-1 (6.57%) and 2-0 (6.15%). The likeliest Wolfsberger win was 1-2 (6.16%), while for a drawn scoreline it was 1-1 (8.35%). The actual scoreline of 4-0 was predicted with a 2.4% likelihood. Our data analysis correctly predicted that Tottenham Hotspur would win this match.
